Sarcopenia and frailty in decompensated cirrhosis

P Tandon, AJ Montano-Loza, JC Lai, S Dasarathy… - Journal of …, 2021‏ - Elsevier
In patients with decompensated cirrhosis, sarcopenia and frailty are prevalent. Although
several definitions exist for these terms, in the field of hepatology, sarcopenia has commonly …

Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy

CF Rose, P Amodio, JS Bajaj, RK Dhiman… - Journal of …, 2020‏ - Elsevier
Hepatic encephalopathy (HE) is a frequent and serious complication of both chronic liver
disease and acute liver failure. HE manifests as a wide spectrum of neuropsychiatric …

Malnutrition, frailty, and sarcopenia in patients with cirrhosis: 2021 practice guidance by the American Association for the Study of Liver Diseases

JC Lai, P Tandon, W Bernal, EB Tapper, U Ekong… - …, 2021‏ - Wiley Online Library
This is the first American Association for the Study of Liver Diseases (AASLD) practice
guidance on the management of malnutrition, frailty, and sarcopenia in patients with …

Sarcopenia, a condition shared by various diseases: can we alleviate or delay the progression?

G Tarantino, G Sinatti, V Citro, SJ Santini… - Internal and Emergency …, 2023‏ - Springer
Sarcopenia is a severe condition common to various chronic diseases and it is reckoned as
a major health problem. It encompasses many different molecular mechanisms that have …

Sarcopenia in cirrhosis: from pathogenesis to interventions

M Ebadi, RA Bhanji, VC Mazurak… - Journal of …, 2019‏ - Springer
Sarcopenia (severe muscle depletion) is a prevalent muscle abnormality in patients with
cirrhosis that confers poor prognosis both pre-and post-liver transplantation. The …

An overview of the molecular mechanisms contributing to musculoskeletal disorders in chronic liver disease: osteoporosis, sarcopenia, and osteoporotic sarcopenia

YJ Yang, DJ Kim - International journal of molecular sciences, 2021‏ - mdpi.com
The prevalence of osteoporosis and sarcopenia is significantly higher in patients with liver
disease than in those without liver disease and osteoporosis and sarcopenia negatively …

Myosteatosis in cirrhosis: a review of diagnosis, pathophysiological mechanisms and potential interventions

M Ebadi, C Tsien, RA Bhanji, AR Dunichand-Hoedl… - Cells, 2022‏ - mdpi.com
Myosteatosis, or pathological excess fat accumulation in muscle, has been widely defined
as a lower mean skeletal muscle radiodensity on computed tomography (CT). It is reported …

[PDF][PDF] Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis

A Kumar, G Davuluri, RN Silva, MPKJ Engelen… - …, 2017‏ - Wiley Online Library
Sarcopenia or skeletal muscle loss is a frequent, potentially reversible complication in
cirrhosis that adversely affects clinical outcomes. Hyperammonemia is a consistent …

Impact of sarcopenia on non-alcoholic fatty liver disease

M Iwaki, T Kobayashi, A Nogami, S Saito, A Nakajima… - Nutrients, 2023‏ - mdpi.com
With the increasing incidence of non-alcoholic fatty liver disease (NAFLD) and the aging of
the population, sarcopenia is attracting attention as one of the pathological conditions …

Non-alcoholic fatty liver disease-related fibrosis and sarcopenia: an altered liver-muscle crosstalk leading to increased mortality risk

MS Kuchay, JI Martínez-Montoro, P Kaur… - Ageing Research …, 2022‏ - Elsevier
In the last few decades, the loss of skeletal muscle mass and function, known as sarcopenia,
has significantly increased in prevalence, becoming a major global public health concern …