Biomolecular sensors for advanced physiological monitoring

CD Flynn, D Chang, A Mahmud, H Yousefi… - Nature Reviews …, 2023 - nature.com
Body-based biomolecular sensing systems, including wearable, implantable and
consumable sensors allow comprehensive health-related monitoring. Glucose sensors have …

Recent advances on emerging biosensing technologies and on-site analytical devices for detection of drug-resistant foodborne pathogens

M Qiu, M Zheng, J Zhang, X Yang, Y Zhang… - TrAC Trends in …, 2023 - Elsevier
The emergence and prevalence of drug-resistant foodborne pathogens have posed a great
threat to food safety and public health. Therefore, rapid, sensitive, reliable, and on-site …

A high-dimensional microfluidic approach for selection of aptamers with programmable binding affinities

D Chang, Z Wang, CD Flynn, A Mahmud, M Labib… - Nature …, 2023 - nature.com
Aptamers are being applied as affinity reagents in analytical applications owing to their high
stability, compact size and amenability to chemical modification. Generating aptamers with …

Bioreceptors as the key components for electrochemical biosensing in medicine

X Wang, J Zhou, H Wang - Cell Reports Physical Science, 2024 - cell.com
With recent advances in point-of-care testing, wearable electronics, and implantable medical
devices, there is a growing interest in develo** state-of-the-art methods to monitor human …

Development of Nucleic‐Acid‐Based Electrochemical Biosensors for Clinical Applications

Z Zhang, P Sen, BR Adhikari, Y Li… - Angewandte …, 2022 - Wiley Online Library
Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

Structural basis for high-affinity recognition of aflatoxin B1 by a DNA aptamer

G Xu, C Wang, H Yu, Y Li, Q Zhao, X Zhou… - Nucleic Acids …, 2023 - academic.oup.com
The 26-mer DNA aptamer (AF26) that specifically binds aflatoxin B1 (AFB1) with nM-level
high affinity is rare among hundreds of aptamers for small molecules. Despite its predicted …

A Colorimetric Biosensing Platform with Aptamers, Rolling Circle Amplification and Urease‐Mediated Litmus Test

D Chang, J Li, R Liu, M Liu, K Tram… - Angewandte …, 2023 - Wiley Online Library
Here we report on an ultra‐sensitive colorimetric sensing platform that takes advantage of
both the strong amplification power of rolling circle amplification (RCA) and the high …

Spatial Engineering of Heterotypic Antigens on a DNA Framework for the Preparation of Mosaic Nanoparticle Vaccines with Enhanced Immune Activation against …

J Zhang, Y Xu, M Chen, S Wang, G Lin… - Angewandte Chemie …, 2024 - Wiley Online Library
Mosaic nanoparticle vaccines with heterotypic antigens exhibit broad‐spectrum antiviral
capabilities, but the impact of antigen proportions and distribution patterns on vaccine …

State-of-the-art electrochemical biosensors based on covalent organic frameworks and their hybrid materials

S **, H Chen, K Pan, R Li, X Ma, R Yuan, X Meng… - Talanta, 2024 - Elsevier
As the development of global population and industry civilization, the accurate and sensitive
detection of intended analytes is becoming an important and great challenge in the field of …

Aptamers for SARS‐CoV‐2: Isolation, Characterization, and Diagnostic and Therapeutic Developments

R Amini, Z Zhang, J Li, J Gu, JD Brennan… - Analysis & …, 2022 - Wiley Online Library
The SARS‐CoV‐2 virus and COVID‐19 pandemic continue to demand effective diagnostic
and therapeutic solutions. Finding these solutions requires highly functional molecular …