On-site bioaerosol sampling and detection in microfluidic platforms

I Lee, E Jeon, J Lee - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
As the recent coronavirus disease (COVID-19) pandemic and several severe illnesses such
as Middle East respiratory syndrome coronavirus (MERS-CoV), Influenza A virus (IAV) flu …

[HTML][HTML] Engineering amyloid and amyloid-like morphologies of β-lactoglobulin

LJG Hoppenreijs, L Fitzner, T Ruhmlieb, TR Heyn… - Food …, 2022 - Elsevier
Background Depending on environmental conditions, almost all proteins can form amyloid
and amyloid-like aggregates that have unique functional properties. This opens numerous …

Spatial control of cell adhesion and patterning through mussel-inspired surface modification by polydopamine

SH Ku, JS Lee, CB Park - Langmuir, 2010 - ACS Publications
The spatial control and patterning of mammalian cells were achieved by using the universal
adhesive property of mussel-inspired polydopamine (PDA). The self-polymerization of …

Biporous silica nanostructure-induced nanovortex in microfluidics for nucleic acid enrichment, isolation, and PCR-free detection

E Jeon, B Koo, S Kim, J Kim, Y Yu, H Jang… - Nature …, 2024 - nature.com
Efficient pathogen enrichment and nucleic acid isolation are critical for accurate and
sensitive diagnosis of infectious diseases, especially those with low pathogen levels. Our …

Vortex-induced formation of insulin amyloid superstructures probed by time-lapse atomic force microscopy and circular dichroism spectroscopy

A Loksztejn, W Dzwolak - Journal of molecular biology, 2010 - Elsevier
Misfolding and aggregation of proteins are multipathway processes that result in
polymorphism of amyloid fibrils. While agitation is one of the most common means of …

Hydrodynamic effects in proteins

P Szymczak, M Cieplak - Journal of Physics: Condensed Matter, 2010 - iopscience.iop.org
Hydrodynamic effects in proteins - IOPscience Skip to content IOP Science home
Accessibility Help Search Journals Journals list Browse more than 100 science journal titles …

Mimicking kidney flow shear efficiently induces aggregation of LECT2, a protein involved in renal amyloidosis

JH Ha, Y Xu, H Sekhon, W Zhao, S Wilkens… - Journal of Biological …, 2024 - ASBMB
Aggregation of leukocyte cell-derived chemotaxin 2 (LECT2) causes ALECT2, a systemic
amyloidosis that affects the kidney and liver. Previous studies established that LECT2 …

Microfluidic approaches for probing amyloid assembly and behaviour

TW Herling, A Levin, KL Saar, CM Dobson… - Lab on a Chip, 2018 - pubs.rsc.org
The self-assembly of proteins into supramolecular structures and machinery underpins
biological activity in living systems. Misassembled, misfolded and aggregated protein …

Microfluidics reveals a flow-induced large-scale polymorphism of protein aggregates

V Foderà, S Pagliara, O Otto, UF Keyser… - The Journal of …, 2012 - ACS Publications
Amyloid fibrils are characterized by a structural arrangement of cross β-sheet as a common
motif. However they can also experience a more complicated packing into a variety of 3D …

High-throughput analysis of alzheimer's β-amyloid aggregation using a microfluidic self-assembly of monomersf

JS Lee, J Ryu, CB Park - Analytical chemistry, 2009 - ACS Publications
The principal histopathological feature of Alzheimer's disease is the presence of β-amyloid
(Aβ) aggregates in the gray matter of the brain, and researchers believe that various …