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Toward explainable artificial intelligence for precision pathology
The rapid development of precision medicine in recent years has started to challenge
diagnostic pathology with respect to its ability to analyze histological images and …
diagnostic pathology with respect to its ability to analyze histological images and …
Combining machine learning and computational chemistry for predictive insights into chemical systems
Machine learning models are poised to make a transformative impact on chemical sciences
by dramatically accelerating computational algorithms and amplifying insights available from …
by dramatically accelerating computational algorithms and amplifying insights available from …
A unifying review of deep and shallow anomaly detection
Deep learning approaches to anomaly detection (AD) have recently improved the state of
the art in detection performance on complex data sets, such as large collections of images or …
the art in detection performance on complex data sets, such as large collections of images or …
AI-based pathology predicts origins for cancers of unknown primary
Cancer of unknown primary (CUP) origin is an enigmatic group of diagnoses in which the
primary anatomical site of tumour origin cannot be determined,. This poses a considerable …
primary anatomical site of tumour origin cannot be determined,. This poses a considerable …
DNA methylation profiling: an emerging paradigm for cancer diagnosis
A Papanicolau-Sengos, K Aldape - Annual Review of Pathology …, 2022 - annualreviews.org
Histomorphology has been a mainstay of cancer diagnosis in anatomic pathology for many
years. DNA methylation profiling is an additional emerging tool that will serve as an adjunct …
years. DNA methylation profiling is an additional emerging tool that will serve as an adjunct …
Designing deep learning studies in cancer diagnostics
The number of publications on deep learning for cancer diagnostics is rapidly increasing,
and systems are frequently claimed to perform comparable with or better than clinicians …
and systems are frequently claimed to perform comparable with or better than clinicians …
Exploring chemical compound space with quantum-based machine learning
Rational design of compounds with specific properties requires understanding and fast
evaluation of molecular properties throughout chemical compound space—the huge set of …
evaluation of molecular properties throughout chemical compound space—the huge set of …
[HTML][HTML] Pruning by explaining: A novel criterion for deep neural network pruning
The success of convolutional neural networks (CNNs) in various applications is
accompanied by a significant increase in computation and parameter storage costs. Recent …
accompanied by a significant increase in computation and parameter storage costs. Recent …
Prediction of DNA methylation-based tumor types from histopathology in central nervous system tumors with deep learning
Precision in the diagnosis of diverse central nervous system (CNS) tumor types is crucial for
optimal treatment. DNA methylation profiles, which capture the methylation status of …
optimal treatment. DNA methylation profiles, which capture the methylation status of …
Ultrasensitive detection of circulating tumour DNA via deep methylation sequencing aided by machine learning
N Liang, B Li, Z Jia, C Wang, P Wu, T Zheng… - Nature biomedical …, 2021 - nature.com
The low abundance of circulating tumour DNA (ctDNA) in plasma samples makes the
analysis of ctDNA biomarkers for the detection or monitoring of early-stage cancers …
analysis of ctDNA biomarkers for the detection or monitoring of early-stage cancers …