Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

Aliphatic polycarbonates have gained increased attention as biomaterials largely owing to
their biocompatibility and tunable degradation. Moreover, the ability to introduce functional …

Biological barriers to drug transport prevent successful accumulation of nanotherapeutics
specifically at diseased sites, limiting efficacious responses in disease processes ranging …

Realization of the immense potential of nanomaterials for biomedical applications will
require a thorough understanding of how they interact with cells, tissues, and organs. There …

The specific sizes that determine optimal nanoparticle tumor accumulation, penetration, and
treatment remain inconclusive because many studies compared nanoparticles with multiple …

Polymer micelles are one of the most investigated nanocarriers for drug delivery; many have
entered clinical trials and some are in clinic use, but their delivery systems have not yet …

The recent remarkable success and safety of mRNA lipid nanoparticle technology for
producing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines has …

Aliphatic polycarbonates have drawn attention as biodegradable polymers that can be
applied to a broad range of resorbable medical devices. In particular, poly (trimethylene …

Cancer is an extremely complex disease involving multiple signaling pathways that enable
tumor cells to evade programmed cell death, thus making cancer treatment extremely …

In rheumatoid arthritis (RA), macrophages infiltrate joints, while fibroblast-like synovial cells
proliferate abnormally, forming a barrier against drug delivery, which hinders effective drug …