Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

Reactive oxygen species (ROS) are pervasive signaling molecules in biological systems. In
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …

Diabetic nephropathy is a diabetic complication caused by chronic inflammation. As the
primary polyphenol in pomegranate, punicalagin is believed to have significant anti …

Macroautophagy/autophagy is a highly conserved process in eukaryotic cells. It plays a
critical role in cellular homeostasis by delivering cytoplasmic cargos to lysosomes for …

In recent years, although the development of clinical therapy for diabetic kidney disease
(DKD) has made great progress, the progression of DKD still cannot be controlled …

There is an increasing interest in the use of nutraceuticals and plant-derived bioactive
compounds from foods for their potential health benefits. For example, as a major active …

Diabetic nephropathy (DN), also named diabetic kidney disease (DKD), is a devastating
complication in patients with both type 1 and 2 diabetes mellitus (T1D and T2D) and its …

Coronavirus disease 2019 (COVID-19) is primarily caused by various forms of severe acute
respiratory syndrome coronavirus type 2 (SARS-CoV-2) variants. COVID-19 is characterized …

Diabetic kidney disease (DKD) is a chronic inflammatory condition that affects approximately
20-40% of individuals with diabetes. Sodium-glucose co-transporter 2 (SGLT-2) inhibitors …

Aims: Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease.
Sodium–glucose cotransporter 2 inhibitors (SGLT2i) showed excellent renoprotective …