ER-phagy and human diseases
Autophagy regulates the degradation of unnecessary or dysfunctional cellular components.
This catabolic process requires the formation of a double-membrane vesicle, the …
This catabolic process requires the formation of a double-membrane vesicle, the …
Staying tight: plasmodesmal membrane contact sites and the control of cell-to-cell connectivity in plants
Multicellularity differs in plants and animals in that the cytoplasm, plasma membrane, and
endomembrane of plants are connected between cells through plasmodesmal pores …
endomembrane of plants are connected between cells through plasmodesmal pores …
MIGA2 links mitochondria, the ER, and lipid droplets and promotes de novo lipogenesis in adipocytes
Physical contact between organelles is vital to the function of eukaryotic cells. Lipid droplets
(LDs) are dynamic organelles specialized in lipid storage that interact physically with …
(LDs) are dynamic organelles specialized in lipid storage that interact physically with …
Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress
S Kanemoto, R Nitani, T Murakami, M Kaneko… - Biochemical and …, 2016 - Elsevier
The endoplasmic reticulum (ER) plays a pivotal role in maintaining cellular homeostasis.
However, numerous environmental and genetic factors give rise to ER stress by inducing an …
However, numerous environmental and genetic factors give rise to ER stress by inducing an …
Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites
The Vps13 protein family is highly conserved in eukaryotic cells. Mutations in human VPS13
genes result in a variety of diseases, such as chorea acanthocytosis (ChAc), but the cellular …
genes result in a variety of diseases, such as chorea acanthocytosis (ChAc), but the cellular …
Multiple C2 domains and transmembrane region proteins (MCTP s) tether membranes at plasmodesmata
ML Brault, JD Petit, F Immel, WJ Nicolas, M Glavier… - EMBO …, 2019 - embopress.org
In eukaryotes, membrane contact sites (MCS) allow direct communication between
organelles. Plants have evolved a unique type of MCS, inside intercellular pores, the …
organelles. Plants have evolved a unique type of MCS, inside intercellular pores, the …
Identification of VAPA and VAPB as Kv2 channel-interacting proteins defining endoplasmic reticulum–plasma membrane junctions in mammalian brain neurons
M Kirmiz, NC Vierra, S Palacio… - Journal of …, 2018 - Soc Neuroscience
Membrane contacts between endoplasmic reticulum (ER) and plasma membrane (PM), or
ER-PM junctions, are ubiquitous in eukaryotic cells and are platforms for lipid and calcium …
ER-PM junctions, are ubiquitous in eukaryotic cells and are platforms for lipid and calcium …
GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells
Endoplasmic reticulum (ER) membrane contact sites (MCSs) are crucial regulatory hubs in
cells, playing roles in signaling, organelle dynamics, and ion and lipid homeostasis …
cells, playing roles in signaling, organelle dynamics, and ion and lipid homeostasis …
Endoplasmic Reticulum–Plasma Membrane Junctions as Sites of Depolarization-Induced Ca2+ Signaling in Excitable Cells
Membrane contact sites between endoplasmic reticulum (ER) and plasma membrane (PM),
or ER-PM junctions, are found in all eukaryotic cells. In excitable cells they play unique roles …
or ER-PM junctions, are found in all eukaryotic cells. In excitable cells they play unique roles …
Tricalbin-mediated contact sites control ER curvature to maintain plasma membrane integrity
J Collado, M Kalemanov, F Campelo, C Bourgoint… - Developmental cell, 2019 - cell.com
Membrane contact sites (MCS) between the endoplasmic reticulum (ER) and the plasma
membrane (PM) play fundamental roles in all eukaryotic cells. ER-PM MCS are particularly …
membrane (PM) play fundamental roles in all eukaryotic cells. ER-PM MCS are particularly …