Chemical diversity in the sialic acids and related α-keto acids: an evolutionary perspective
The glycan chains of vertebrate glycoconjugates are composed mostly of five-and six-
carbon sugars. One striking exception is the family of sialic acids (Sia), which are R-keto …
carbon sugars. One striking exception is the family of sialic acids (Sia), which are R-keto …
Phase and antigenic variation in bacteria
Phase and antigenic variation result in a heterogenic phenotype of a clonal bacterial
population, in which individual cells either express the phase-variable protein (s) or not, or …
population, in which individual cells either express the phase-variable protein (s) or not, or …
Advances in the biology and chemistry of sialic acids
Sialic acids are a subset of nonulosonic acids, which are nine-carbon α-keto aldonic acids.
Natural existing sialic acid-containing structures are presented in different sialic acid forms …
Natural existing sialic acid-containing structures are presented in different sialic acid forms …
Sialic acid utilization by bacterial pathogens
E Severi, DW Hood, GH Thomas - Microbiology, 2007 - microbiologyresearch.org
Sialic acid occupies the terminal position within glycan molecules on the surfaces of many
vertebrate cells, where it functions in diverse cellular processes such as intercellular …
vertebrate cells, where it functions in diverse cellular processes such as intercellular …
Sialic acid and biology of life: An introduction
S Ghosh - Sialic acids and sialoglycoconjugates in the biology …, 2020 - pmc.ncbi.nlm.nih.gov
Sialic acids are important molecule with high structural diversity. They are known to occur in
higher animals such as Echinoderms, Hemichordata, Cephalochorda, and Vertebrata and …
higher animals such as Echinoderms, Hemichordata, Cephalochorda, and Vertebrata and …
The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach
A Harduin-Lepers, R Mollicone, P Delannoy… - …, 2005 - academic.oup.com
The animal sialyltransferases are Golgi type II transmembrane glycosyltransferases. Twenty
distinct sialyltransferases have been identified in both human and murine genomes. These …
distinct sialyltransferases have been identified in both human and murine genomes. These …
To sialylate, or not to sialylate: that is the question
E Vimr, C Lichtensteiger - Trends in microbiology, 2002 - cell.com
Most oropharyngeal pathogens express sialic acid units on their surfaces, mimicking the
sialyl-rich mucin layer coating epithelial cells and the glycoconjugates present on virtually all …
sialyl-rich mucin layer coating epithelial cells and the glycoconjugates present on virtually all …
Haemophilus influenzae Forms Biofilms on Airway Epithelia: Implications in Cystic Fibrosis
TD Starner, N Zhang, GH Kim, MA Apicella… - American journal of …, 2006 - atsjournals.org
Rationale: Nontypeable Haemophilus influenzae (NTHi) commonly infects patients with
cystic fibrosis (CF), especially early in childhood. Bacteria biofilms are increasingly …
cystic fibrosis (CF), especially early in childhood. Bacteria biofilms are increasingly …
Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media
V Bouchet, DW Hood, J Li, JR Brisson… - Proceedings of the …, 2003 - pnas.org
Otitis media, a common and often recurrent bacterial infection of childhood, is a major
reason for physician visits and the prescription of antimicrobials. Haemophilus influenzae is …
reason for physician visits and the prescription of antimicrobials. Haemophilus influenzae is …
Antecedent infections in Fisher syndrome: a common pathogenesis of molecular mimicry
Objective: To assess the production mechanism of anti-GQ1b autoantibody in Fisher
syndrome (FS). Methods: The authors conducted a prospective case-control serologic study …
syndrome (FS). Methods: The authors conducted a prospective case-control serologic study …