Clinical trials with mesenchymal stem cells: an update
T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
Role of neuroinflammation in amyotrophic lateral sclerosis: cellular mechanisms and therapeutic implications
J Liu, F Wang - Frontiers in immunology, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects
upper motor neurons (MNs) comprising the corticospinal tract and lower MNs arising from …
upper motor neurons (MNs) comprising the corticospinal tract and lower MNs arising from …
Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
Experimental autoimmune encephalomyelitis (EAE) is the most commonly used
experimental model for the human inflammatory demyelinating disease, multiple sclerosis …
experimental model for the human inflammatory demyelinating disease, multiple sclerosis …
Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis
D Karussis, C Karageorgiou… - Archives of …, 2010 - jamanetwork.com
Objective To evaluate the feasibility, safety, and immunological effects of intrathecal and
intravenous administration of autologous mesenchymal stem cells (MSCs)(also …
intravenous administration of autologous mesenchymal stem cells (MSCs)(also …
Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis
I Kassis, N Grigoriadis, B Gowda-Kurkalli… - Archives of …, 2008 - jamanetwork.com
Objective To investigate the therapeutic potential of mesenchymal stromal cells (MSCs) in
the chronic model of experimental autoimmune encephalomyelitis (EAE). Design …
the chronic model of experimental autoimmune encephalomyelitis (EAE). Design …
Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells
Regenerative processes occurring under physiological (maintenance) and pathological
(reparative) conditions are a fundamental part of life and vary greatly among different …
(reparative) conditions are a fundamental part of life and vary greatly among different …
Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2, 3 dioxygenase (IDO)
The kynurenine pathway (KP) of tryptophan metabolism is linked to antimicrobial activity and
modulation of immune responses but its role in stem cell biology is unknown. We show that …
modulation of immune responses but its role in stem cell biology is unknown. We show that …
Animal models of multiple sclerosis—potentials and limitations
E Mix, H Meyer-Rienecker, HP Hartung… - Progress in neurobiology, 2010 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is still the most widely accepted animal
model of multiple sclerosis (MS). Different types of EAE have been developed in order to …
model of multiple sclerosis (MS). Different types of EAE have been developed in order to …
Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression
Objective Intracerebroventricular or intravenous (IV) injection of neural precursor cells
(NPCs) attenuates experimental autoimmune encephalomyelitis (EAE), the animal model of …
(NPCs) attenuates experimental autoimmune encephalomyelitis (EAE), the animal model of …
Human neural stem cells ameliorate autoimmune encephalomyelitis in non‐human primates
Objective Transplanted neural stem/precursor cells (NPCs) display peculiar therapeutic
plasticity in vivo. Although the replacement of cells was first expected as the prime …
plasticity in vivo. Although the replacement of cells was first expected as the prime …