Podocytopathies are kidney diseases in which direct or indirect podocyte injury drives
proteinuria or nephrotic syndrome. In children and young adults, genetic variants in> 50 …

The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

A cyclical corticosteroid-cyclophosphamide regimen is recommended for patients with
primary membranous nephropathy at high risk of progression. We hypothesized that …

Rituximab induces nephrotic syndrome (NS) remission in two-thirds of patients with primary
membranous nephropathy (MN), even after other treatments have failed. To assess the …

Most glomerulonephritides, even the more common types, are rare diseases. They are
nevertheless important since they frequently affect young people, often cannot be cured, and …

Background Rituximab could be an effective treatment for childhood-onset, complicated,
frequently relapsing nephrotic syndrome (FRNS) and steroid-dependent nephrotic …

Focal segmental glomerulosclerosis (FSGS) is a histological pattern of glomerular injury,
rather than a single disease, that is caused by diverse clinicopathological entities with …

Nephrotic syndrome is defined by nephrotic-range proteinuria (≥ 40 mg/m2/hour or urine
protein/creatinine ratio≥ 200 mg/mL or 3+ protein on urine dipstick), hypoalbuminaemia (< …

Background Long-term outcomes after multiple courses of rituximab among children with
frequently relapsing, steroid-dependent nephrotic syndrome (FRSDNS) are unknown …