Guillain-barré syndrome

N Shahrizaila, HC Lehmann, S Kuwabara - The lancet, 2021 - thelancet.com
Guillain-Barré syndrome is the most common cause of acute flaccid paralysis worldwide.
Most patients present with an antecedent illness, most commonly upper respiratory tract …

[HTML][HTML] Diagnosis and management of Guillain–Barré syndrome in ten steps

SE Leonhard, MR Mandarakas, FAA Gondim… - Nature Reviews …, 2019 - nature.com
Guillain–Barré syndrome (GBS) is a rare, but potentially fatal, immune-mediated disease of
the peripheral nerves and nerve roots that is usually triggered by infections. The incidence of …

European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of Guillain–Barré syndrome

PA van Doorn, PYK Van den Bergh… - Journal of the …, 2023 - Wiley Online Library
Guillain–Barré syndrome (GBS) is an acute polyradiculoneuropathy. Symptoms may vary
greatly in presentation and severity. Besides weakness and sensory disturbances, patients …

Complement in neurological disorders and emerging complement-targeted therapeutics

MC Dalakas, H Alexopoulos, PJ Spaeth - Nature Reviews Neurology, 2020 - nature.com
The complement system consists of a network of plasma and membrane proteins that
modulate tissue homeostasis and contribute to immune surveillance by interacting with the …

Tip** the balance: intricate roles of the complement system in disease and therapy

RB Pouw, D Ricklin - Seminars in Immunopathology, 2021 - Springer
The ability of the complement system to rapidly and broadly react to microbial intruders,
apoptotic cells and other threats by inducing forceful elimination responses is indispensable …

Immune-mediated neuropathies

BC Kieseier, EK Mathey, C Sommer… - Nature reviews Disease …, 2018 - nature.com
Since the discovery of an acute monophasic paralysis, later coined Guillain–Barré
syndrome, almost 100 years ago, and the discovery of chronic, steroid-responsive …

Intensive care and treatment of severe Guillain–Barré syndrome

P Shang, J Feng, W Wu, HL Zhang - Frontiers in pharmacology, 2021 - frontiersin.org
Guillain–Barré syndrome (GBS) is an acute polyneuropathy mostly characterized by acute
flaccid paralysis with or without sensory/autonomous nerve dysfunction. Current immuno …

Immune-mediated neuropathies: pathophysiology and management

A Shastri, A Al Aiyan, U Kishore… - International journal of …, 2023 - mdpi.com
Dysfunction of the immune system can result in damage of the peripheral nervous system.
The immunological mechanisms, which include macrophage infiltration, inflammation and …

Novel immunological and therapeutic insights in Guillain-Barré syndrome and CIDP

L Querol, C Lleixà - Neurotherapeutics, 2021 - Springer
Inflammatory neuropathies are a heterogeneous group of rare diseases of the peripheral
nervous system that include acute and chronic diseases, such as Guillain-Barré syndrome …

[HTML][HTML] Therapeutic monoclonal antibody therapies in chronic autoimmune demyelinating neuropathies

C Briani, A Visentin - Neurotherapeutics, 2022 - Elsevier
Autoimmune diseases of the peripheral nervous system have so far been treated mainly with
exogenous high-dose intravenous immunoglobulins (IVIg), that act through several …