Hepatocellular carcinoma (HCC), the primary malignancy of hepatocytes, is a diagnosis with
bleak outcome. According to National Cancer Institute's SEER database, the average five …

Liver fibrosis is the final common pathway of chronic or iterative liver damage. Advanced
chronic fibrosis is described as cirrhosis with a loss of architecture and attendant functional …

Alcoholic liver disease (ALD) has been among the leading causes of cirrhosis and liver-
related death worldwide for decades. Early discoveries in alcoholic liver disease identified …

Alcohol affects many organs, including the immune system, with even moderate amounts of
alcohol influencing immune responses. Although alcohol can alter the actions of all cell …

Conclusions Metabolomic signatures identify three NAFLD subgroups, independent of
histological disease severity. These signatures align with known CVD and genetic risk …

Background & Aims Alcoholic liver disease (ALD) ranges from fatty liver to inflammation and
cirrhosis. miRNA-155 is an important regulator of inflammation. In this study, we describe the …

Alcoholic liver disease (ALD) represents a spectrum of injury, ranging from simple steatosis
to alcoholic hepatitis to cirrhosis. Regular alcohol use results in fatty changes in the liver …

Liver fibrosis occurs as a wound‐healing scar response following chronic liver inflammation
including alcoholic liver disease, non‐alcoholic steatohepatitis, viral hepatitis, cholestatic …

Systemic and local inflammation in relation to the resident microbiota of the human gastro-
intestinal (GI) tract and administration of probiotics are the main themes of the present …

Cellular homeostais, that is normally maintained through autophagy, is disrupted in
alcoholic liver disease (ALD). Because autophagy and exosome biogenesis share common …