Histone deacetylase functions and therapeutic implications for adult skeletal muscle metabolism

S Molinari, C Imbriano, V Moresi, A Renzini… - Frontiers in Molecular …, 2023 - frontiersin.org
Skeletal muscle is a highly adaptive organ that sustains continuous metabolic changes in
response to different functional demands. Healthy skeletal muscle can adjust fuel utilization …

A mechanism-based perspective on the use of flavonoids in the treatment of diabetes and its complications

SK Pattanaik, MP Anil, S Jena… - Current Diabetes …, 2024 - benthamdirect.com
Diabetes is a chronic, irreversible, non-infectious metabolic syndrome associated with low
insulin production by the pancreas or due to insulin resistance. The management landscape …

Flavonoids quercetin and kaempferol are NR4A1 antagonists and suppress endometriosis in female mice

L Zhang, K Mohankumar, G Martin, F Mariyam… - …, 2023 - academic.oup.com
Abstract Nuclear receptor 4A1 (NR4A1) plays an important role in endometriosis
progression; levels of NR4A1 in endometriotic lesions are higher than in normal …

[HTML][HTML] Improvement of glucolipid metabolism and oxidative stress via modulating PI3K/Akt pathway in insulin resistance HepG2 cells by chickpea flavonoids

K Zhou, S **ao, S Cao, C Zhao, M Zhang, Y Fu - Food Chemistry: X, 2024 - Elsevier
Chickpea (Cicer arietinum L.) is a significant dietary source of flavonoids and the
hypoglycemic activity were investigated in this study. Firstly, total twenty nine chickpea …

Black mulberry extract inhibits hepatic adipogenesis through AMPK/mTOR signaling pathway in T2DM mice

Y Yao, Y Chen, H Chen, X Pan, X Li, W Liu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Black mulberry (Morus nigra L.) is an ancient dual-
use plant resource for medicine and food. It is widely used in Uyghur folklore for …

Potential of Laurel (Laurus nobilis L.) Leaf Polyphenols for Modulation of Body Composition

E Dobroslavić, I Elez Garofulić, JZ Ilich - Applied Sciences, 2023 - mdpi.com
Featured Application Based on the properties evaluated in this review, laurel leaf
polyphenols could promote healthy aging by preventing or abating various metabolic …

Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction

SA Ahmed, JC Borah, P Manna - RSC Medicinal Chemistry, 2024 - pubs.rsc.org
Metabolic syndrome is a multifaceted condition marked by interconnected risk factors,
significantly increasing the risk of serious diseases like cardiovascular disease, type 2 …

Chemical and biochemical characterization of Ipomoea aquatica: genoprotective potential and inhibitory mechanism of its phytochemicals against α-amylase and α …

K Saikia, S Dey, SN Hazarika, GK Handique… - Frontiers in …, 2023 - frontiersin.org
Ipomea aquatica, also known as water spinach, is an aquatic non-conventional leafy
vegetable and is considered a healthy and seasonal delicacy in ethnic food culture. The …

[HTML][HTML] Effect of Ficus pumila L. on Improving Insulin Secretory Capacity and Resistance in Elderly Patients Aged 80 Years Old or Older Who Develop Diabetes After …

K Gonda, T Hai, K Suzuki, A Ozaki, T Shibusa… - Nutrients, 2025 - mdpi.com
(1) Background: It has been reported that people affected by COVID-19, an infectious
disease caused by SARS-CoV-2, suffer from various diseases, after infection. One of the …

Sirtuins as Players in the Signal Transduction of Citrus Flavonoids

GE Lombardo, C Russo, A Maugeri… - International Journal of …, 2024 - mdpi.com
Sirtuins (SIRTs) belong to the family of nicotine adenine dinucleotide (NAD+)-dependent
class III histone deacetylases, which come into play in the regulation of epigenetic …