Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy
M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …
pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects
LJC Albuquerque, V Sincari, A Jäger, J Kucka… - Journal of Controlled …, 2021 - Elsevier
The delivery of therapeutics into sites of action by using cargo-delivery platforms potentially
minimizes their premature degradation and fast clearance from the bloodstream …
minimizes their premature degradation and fast clearance from the bloodstream …
The in vivo fate of 225Ac daughter nuclides using polymersomes as a model carrier
RM Kruijff, R Raavé, A Kip, J Molkenboer-Kuenen… - Scientific reports, 2019 - nature.com
Increasing attention is given to personalized tumour therapy, where α-emitters can
potentially play an important role. Alpha particles are ideal for localized cell killing because …
potentially play an important role. Alpha particles are ideal for localized cell killing because …
Microfluidic-assisted engineering of quasi-monodisperse pH-responsive polymersomes toward advanced platforms for the intracellular delivery of hydrophilic …
LJC Albuquerque, V Sincari, A Ja? ger, R Konefa?… - Langmuir, 2019 - ACS Publications
The extracellular and subcellular compartments are characterized by specific pH levels that
can be modified by pathophysiological states. This scenario encourages the use of …
can be modified by pathophysiological states. This scenario encourages the use of …
[HTML][HTML] Deep learning for automatic organ and tumor segmentation in nanomedicine pharmacokinetics
Rationale: Multimodal imaging provides important pharmacokinetic and dosimetry
information during nanomedicine development and optimization. However, accurate …
information during nanomedicine development and optimization. However, accurate …
99mTc Radiolabeled HA/TPGS-Based Curcumin-Loaded Nanoparticle for Breast Cancer Synergistic Theranostics: Design, in vitro and in vivo Evaluation
C Huang, F Chen, L Zhang, Y Yang… - International journal of …, 2020 - Taylor & Francis
Background Emerging cancer therapy requires highly sensitive diagnosis in combination
with cancer-targeting therapy. In this study, a self-assembled pH-sensitive curcumin (Cur) …
with cancer-targeting therapy. In this study, a self-assembled pH-sensitive curcumin (Cur) …
[HTML][HTML] Uptake and subcellular distribution of radiolabeled polymersomes for radiotherapy
Polymersomes have the potential to be applied in targeted alpha radionuclide therapy, while
in addition preventing release of recoiling daughter isotopes. In this study, we investigated …
in addition preventing release of recoiling daughter isotopes. In this study, we investigated …
Elucidating the influence of tumor presence on the polymersome circulation time in mice
RM de Kruijff, R Raavé, A Kip, J Molkenboer-Kuenen… - Pharmaceutics, 2019 - mdpi.com
The use of nanoparticles as tumor-targeting agents is steadily increasing, and the influence
of nanoparticle characteristics such as size and stealthiness have been established for a …
of nanoparticle characteristics such as size and stealthiness have been established for a …
Self-assembled polymer systems responsive to external stimuli for biomedicine
V Sincari - 2022 - dspace.cuni.cz
The first work in my doctoral thesis described a novel rapid and eco-friendly reversible
addition-fragmentation chain transfer (RAFT) polymerization reaction of the N-(2 …
addition-fragmentation chain transfer (RAFT) polymerization reaction of the N-(2 …
[PDF][PDF] Федеральное государственное бюджетное учреждение науки ФИЗИКО-ТЕХНИЧЕСКИЙ ИНСТИТУТ им. АФ ИОФФЕ Российской академии наук
ВПК НАНОКРИСТАЛЛАХ - ioffe.ru
Актуальность темы исследования. Полупроводниковые коллоидные на нокристаллы в
стекле [1, 2] и в водном растворе [3] были впервые синтезированы более 30 лет назад …
стекле [1, 2] и в водном растворе [3] были впервые синтезированы более 30 лет назад …