Data-independent acquisition (DIA) mass spectrometry (MS) has emerged as a powerful
technology for high-throughput, accurate, and reproducible quantitative proteomics. This …

According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

De novo peptide sequencing from tandem MS data is the key technology in proteomics for
the characterization of proteins, especially for new sequences, such as mAbs. In this study …

Integrating data-dependent acquisition (DDA) and data-independent acquisition (DIA)
approaches can enable highly sensitive mass spectrometry, especially for …

ProLuCID, a new algorithm for peptide identification using tandem mass spectrometry and
protein sequence databases has been developed. This algorithm uses a three tier scoring …

This manuscript provides a comprehensive review of the peptide and protein identification
process using tandem mass spectrometry (MS/MS) data generated in shotgun proteomic …

De novo sequencing software has been widely used in proteomics to sequence new
peptides from tandem mass spectrometry data. This study presents a new software tool …

Novel protein discovery and immunopeptidomics depend on highly sensitive de novo
peptide sequencing with tandem mass spectrometry. Despite notable improvement using …

Although mass spectrometry is well suited to identifying thousands of potential protein post-
translational modifications (PTMs), it has historically been biased towards just a few. To …

Mass spectrometry has become the method of choice for the qualitative and quantitative
characterization of protein mixtures isolated from all kinds of living organisms. The raw data …