There is a growing attention toward personalized medicine. This is led by a fundamental
shift from the 'one size fits all'paradigm for treatment of patients with conditions or …

Prioritization of immunogenic neoantigens is key to enhancing cancer immunotherapy
through the development of personalized vaccines, adoptive T cell therapy, and the …

BACKGROUND Adenoid cystic carcinoma (ACC) is a rare malignancy arising in salivary
glands and other sites, characterized by high rates of relapse and distant spread …

DNA variants represent an important source of genetic variations among individuals. Next-
generation sequencing (NGS) is the most popular technology for genome-wide variant …

Motivation Accurate detection, genoty** and downstream analysis of genomic variants
from high-throughput sequencing data are fundamental features in modern production …

Molecular profiling of tumor biopsies plays an increasingly important role not only in cancer
research, but also in the clinical management of cancer patients. Multi-omics approaches …

Blood biochemical indicators play a crucial role in assessing an individual's overall health
status and metabolic function. In this study, we measured five blood biochemical indicators …

The lack of samples for generating standardized DNA datasets for setting up a sequencing
pipeline or benchmarking the performance of different algorithms limits the implementation …

Breast cancer is a disease of genomic alterations, of which the panorama of somatic
mutations and how these relate to subtypes and therapy response is incompletely …

Today, whole-exome sequencing (WES) is used to conduct the massive screening of
structural and regulatory genes in order to identify the allele frequencies of disease …