Label-free microfluidic cell sorting and detection for rapid blood analysis
N Lu, HM Tay, C Petchakup, L He, L Gong, KK Maw… - Lab on a Chip, 2023 - pubs.rsc.org
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …
Atomic force microscopy-based force spectroscopy and multiparametric imaging of biomolecular and cellular systems
During the last three decades, a series of key technological improvements turned atomic
force microscopy (AFM) into a nanoscopic laboratory to directly observe and chemically …
force microscopy (AFM) into a nanoscopic laboratory to directly observe and chemically …
Mechanical adaptability of tumor cells in metastasis
The most dangerous aspect of cancer lies in metastatic progression. Tumor cells will
successfully form life-threatening metastases when they undergo sequential steps along a …
successfully form life-threatening metastases when they undergo sequential steps along a …
Single-cell microfluidic impedance cytometry: From raw signals to cell phenotypes using data analytics
The biophysical analysis of single-cells by microfluidic impedance cytometry is emerging as
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …
The extracellular matrix viscoelasticity as a regulator of cell and tissue dynamics
A Elosegui-Artola - Current opinion in cell biology, 2021 - Elsevier
The extracellular matrix mechanical properties regulate processes in development, cancer,
and fibrosis. Among the distinct mechanical properties, the vast majority of research has …
and fibrosis. Among the distinct mechanical properties, the vast majority of research has …
Microfluidic technologies for cell deformability cytometry
Microfluidic detection methods for cell deformability cytometry have been regarded as
powerful tools for single‐cell analysis of cellular mechanical phenotypes, thus having been …
powerful tools for single‐cell analysis of cellular mechanical phenotypes, thus having been …
Computer vision meets microfluidics: a label-free method for high-throughput cell analysis
S Zhou, B Chen, ES Fu, H Yan - Microsystems & Nanoengineering, 2023 - nature.com
In this paper, we review the integration of microfluidic chips and computer vision, which has
great potential to advance research in the life sciences and biology, particularly in the …
great potential to advance research in the life sciences and biology, particularly in the …
Mechanical properties of single cells: Measurement methods and applications
Cell mechanical properties, eg elastic and shear modulus, play vital roles in cell activities
and functions, such as cell growth, cell division, cell motion, and cell adhesion …
and functions, such as cell growth, cell division, cell motion, and cell adhesion …
Impedance‐Based Multimodal Electrical‐Mechanical Intrinsic Flow Cytometry
Reflecting various physiological states and phenotypes of single cells, intrinsic biophysical
characteristics (eg, mechanical and electrical properties) are reliable and important, label …
characteristics (eg, mechanical and electrical properties) are reliable and important, label …
Viscoelastic properties of suspended cells measured with shear flow deformation cytometry
Numerous cell functions are accompanied by phenotypic changes in viscoelastic properties,
and measuring them can help elucidate higher level cellular functions in health and disease …
and measuring them can help elucidate higher level cellular functions in health and disease …