Advances and challenges in sepsis management: modern tools and future directions

E Santacroce, M D'Angerio, AL Ciobanu, L Masini… - Cells, 2024 - mdpi.com
Sepsis, a critical condition marked by systemic inflammation, profoundly impacts both innate
and adaptive immunity, often resulting in lymphopenia. This immune alteration can spare …

[HTML][HTML] AI and machine learning in resuscitation: Ongoing research, new concepts, and key challenges

Y Okada, M Mertens, N Liu, SSW Lam, MEH Ong - Resuscitation plus, 2023 - Elsevier
Aim Artificial intelligence (AI) and machine learning (ML) are important areas of computer
science that have recently attracted attention for their application to medicine. However, as …

[HTML][HTML] Clinical sepsis phenotypes in critically ill patients

G Papathanakos, I Andrianopoulos, M Xenikakis… - Microorganisms, 2023 - mdpi.com
Sepsis, defined as the life-threatening dysregulated host response to an infection leading to
organ dysfunction, is considered as one of the leading causes of mortality worldwide …

The persistent inflammation, immunosuppression, and catabolism syndrome 10 years later

PA Efron, SC Brakenridge, AM Mohr… - Journal of Trauma …, 2023 - journals.lww.com
Sepsis and trauma were the primary inciting events. With tremendous the advances in care
over the ensuing four decades, the epidemiology of MOF evolved from a fulminant …

Non-generative artificial intelligence (AI) in medicine: advancements and applications in supervised and unsupervised machine learning

L Pantanowitz, T Pearce, I Abukhiran, M Hanna… - Modern Pathology, 2024 - Elsevier
Abstract The use of Artificial Intelligence (AI) within pathology and healthcare has advanced
extensively. We have accordingly witnessed increased adoption of various AI tools which …

Clinical phenotype classification to predict risk and optimize the management of patients with atrial fibrillation using the Atrial Fibrillation Better Care (ABC) pathway: a …

R Krittayaphong, S Treewaree… - … Journal of Medicine, 2024 - academic.oup.com
Background Phenotypic classification is a method of grou** patients with similar
phenotypes. Aim We aimed to use phenotype classification based on a clustering process …

Categorical data clustering: 25 years beyond K-modes

T Dinh, W Hauchi, P Fournier-Viger, D Lisik… - Expert Systems with …, 2025 - Elsevier
The clustering of categorical data is a common and important task in computer science,
offering profound implications across a spectrum of applications. Unlike purely numerical …

Phenotype of new daily persistent headache: subtypes and comparison to transformed chronic daily headache

S Cheema, A Stubberud, K Rantell, P Nachev… - The Journal of …, 2023 - Springer
Background It is unknown whether new daily persistent headache (NDPH) is a single
disorder or heterogenous group of disorders, and whether it is a unique disorder from …

Six clinical phenotypes with prognostic implications were identified by unsupervised machine learning in children and adolescents with SARS-CoV-2 infection: results …

Y Shi, R Strobl, R Berner, J Armann, S Scheithauer… - Respiratory …, 2024 - Springer
Objective Phenotypes are important for patient classification, disease prognostication, and
treatment customization. We aimed to identify distinct clinical phenotypes of children and …

Cardiometabolic and renal phenotypes and transitions in the United States population

VPF Lhoste, B Zhou, A Mishra, JE Bennett… - Nature cardiovascular …, 2024 - nature.com
Cardiovascular and renal conditions have both shared and distinct determinants. In this
study, we applied unsupervised clustering to multiple rounds of the National Health and …