Role of sugar osmolytes and their nano-counterparts as inhibitors in protein fibrillation

D Alam, F Naaz, A Islam, M Sardar, T Ahmad - Journal of Molecular Liquids, 2023 - Elsevier
Protein aggregation is responsible for various human diseases, ie Alzheimer's, Parkinson's,
Huntington's as well as cataract. Finding molecular drugs which could prevent protein …

Cholinium-based ionic liquids attenuate the amyloid fibril formation of lysozyme: a greener concept of antiamyloidogenic ionic liquids

A Sindhu, RS Varma, P Venkatesu - ACS Sustainable Chemistry …, 2022 - ACS Publications
Amyloid fibrils share dominant β-sheet structures that form pathological deposits in human
organs causing various debilitating neurodegenerative diseases such as type II diabetes …

Effects of amino acid-functionalized silver nanoparticles on lysozyme amyloid fibrillogenesis

SS Lu, YR Lai, LH Hsiao, HY Huang, YH Tsai… - Colloids and Surfaces B …, 2023 - Elsevier
Highlights•Proline-/cysteine-modified silver nanoparticles (Pro-/Cys-AgNP) were
prepared.•Pro-AgNP/Cys-AgNP dose-dependently suppresses lysozyme amyloid fibril …

Depolymerization of insulin amyloid fibrils by albumin-modified magnetic fluid

K Siposova, M Kubovcikova, Z Bednarikova… - …, 2012 - iopscience.iop.org
Pathogenesis of amyloid-related diseases is associated with the presence of protein
amyloid deposits. Insulin amyloids have been reported in a patient with diabetes undergoing …

Delineating the effect of trehalose nanoparticles on aggregation pattern of apo-α-lactalbumin protein: A nano-approach towards counteracting proteinopathies

D Alam, T Khan, F Naaz, T Ahmad, M Shahid… - Journal of Molecular …, 2025 - Elsevier
Investigation of protein aggregation is a challenging and daunting task as it is associated
with many amyloid-related diseases like Alzheimer's, Parkinson's diseases, etc. Sugar …

Examining the inhibitory potency of metal polyphenolic network–coated silver nanoparticles against amyloid fibrillogenesis of lysozyme

YH Kung, CY Chang, YR Lai, JX Li, SC How - Spectrochimica Acta Part A …, 2025 - Elsevier
There are currently over forty degenerative diseases that are correlated with abnormal
accumulation of peptide/protein aggregates in the human body, such as Alzheimer's …

Encapsulation with a complex of acidic/alkaline polysaccharide-whey protein isolate fibril bilayer microcapsules enhances the stability of β-carotene under acidic …

YY Yang, YR Lai, SC How, TH Lin… - Journal of the Taiwan …, 2024 - Elsevier
Background Recent studies have highlighted the potential of protein fibrils for the
microencapsulation of lipophilic bioactive molecules. Given their biocompatible and …

Auto-fluorescência em processos de agregação de péptidos e proteínas: beta-amilóide na presença de iões e lisozima sob condições promotoras de agregação

BRM Coutinho - 2022 - estudogeral.uc.pt
O estudo do mecanismo de formação de agregados proteicos é atualmente alvo de
interesse devido à sua frequente relação com doenças neurológicas como o Alzheimer …