The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

[HTML][HTML] Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases

C Gubert, G Kong, T Renoir, AJ Hannan - Neurobiology of disease, 2020 - Elsevier
The last decade has witnessed an exponentially growing interest in gut microbiota and the
gut-brain axis in health and disease. Accumulating evidence from preclinical and clinical …

[HTML][HTML] Ketogenic diet in Alzheimer's disease

M Rusek, R Pluta, M Ułamek-Kozioł… - International journal of …, 2019 - mdpi.com
At present, the prevalence of Alzheimer's disease, a devastating neurodegenerative
disorder, is increasing. Although the mechanism of the underlying pathology is not fully …

[HTML][HTML] Role of ketogenic diets in neurodegenerative diseases (Alzheimer's disease and Parkinson's disease)

D Włodarek - Nutrients, 2019 - mdpi.com
The goal of this review was to assess the effectiveness of ketogenic diets on the therapy of
neurodegenerative diseases. The ketogenic diet is a low-carbohydrate and fat-rich diet. Its …

Regulation of ketone body metabolism and the role of PPARα

M Grabacka, M Pierzchalska, M Dean… - International journal of …, 2016 - mdpi.com
Ketogenesis and ketolysis are central metabolic processes activated during the response to
fasting. Ketogenesis is regulated in multiple stages, and a nuclear receptor peroxisome …

Metabolic reprograming of microglia in the regulation of the innate inflammatory response

C Lauro, C Limatola - Frontiers in Immunology, 2020 - frontiersin.org
Microglia sustain normal brain functions continuously monitoring cerebral parenchyma to
detect neuronal activities and alteration of homeostatic processes. The metabolic pathways …

[HTML][HTML] Anti-oxidant and anti-inflammatory activity of ketogenic diet: new perspectives for neuroprotection in Alzheimer's disease

A Pinto, A Bonucci, E Maggi, M Corsi, R Businaro - Antioxidants, 2018 - mdpi.com
The ketogenic diet, originally developed for the treatment of epilepsy in non-responder
children, is spreading to be used in the treatment of many diseases, including Alzheimer's …

Sustainable applications of polyhydroxyalkanoates in various fields: A critical review

A Pandey, N Adama, K Adjallé, JF Blais - International Journal of Biological …, 2022 - Elsevier
PHA is one of the most promising candidates in bio-polymer family which is biodegradable
and environment-friendly in nature. In recent years, it has been applied as a biodegradable …

Bioenergetic regulation of microglia

S Ghosh, E Castillo, ES Frias, RA Swanson - Glia, 2018 - Wiley Online Library
Microglia have diverse actions, ranging from synapse pruning in development to cytotoxic
effects in disease. Brain energy metabolism and substrate availability vary under normal and …

The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages

M Rahman, S Muhammad, MA Khan, H Chen… - Nature …, 2014 - nature.com
The ketone body β-hydroxybutyrate (BHB) is an endogenous factor protecting against stroke
and neurodegenerative diseases, but its mode of action is unclear. Here we show in a stroke …