Epilepsy in adults
Epilepsy is one of the most common serious brain conditions, affecting over 70 million
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …
Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention
O Devinsky, DC Hesdorffer, DJ Thurman… - The Lancet …, 2016 - thelancet.com
Sudden unexpected death in epilepsy (SUDEP) can affect individuals of any age, but is most
common in younger adults (aged 20–45 years). Generalised tonic-clonic seizures are the …
common in younger adults (aged 20–45 years). Generalised tonic-clonic seizures are the …
The SANTÉ study at 10 years of follow‐up: effectiveness, safety, and sudden unexpected death in epilepsy
V Salanova, MR Sperling, RE Gross, CP Irwin… - …, 2021 - Wiley Online Library
Objective We evaluated the efficacy and safety of deep brain anterior thalamus stimulation
after 7 and 10 years, and report the incidence of sudden unexpected death in epilepsy …
after 7 and 10 years, and report the incidence of sudden unexpected death in epilepsy …
Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy
DR Nair, KD Laxer, PB Weber, AM Murro, YD Park… - Neurology, 2020 - AAN Enterprises
Objective To prospectively evaluate safety and efficacy of brain-responsive neurostimulation
in adults with medically intractable focal onset seizures (FOS) over 9 years. Methods Adults …
in adults with medically intractable focal onset seizures (FOS) over 9 years. Methods Adults …
Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and risk factors: Report of the Guideline Development, Dissemination, and …
C Harden, T Tomson, D Gloss, J Buchhalter, JH Cross… - Neurology, 2017 - AAN Enterprises
Objective: To determine the incidence rates of sudden unexpected death in epilepsy
(SUDEP) in different epilepsy populations and address the question of whether risk factors …
(SUDEP) in different epilepsy populations and address the question of whether risk factors …
Clinical risk factors in SUDEP: a nationwide population-based case-control study
Objective We conducted a nationwide case-control study in Sweden to test the hypothesis
that specific clinical characteristics are associated with increased risk of sudden unexpected …
that specific clinical characteristics are associated with increased risk of sudden unexpected …
Epilepsy: new advances
Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …
[HTML][HTML] The consequences of refractory epilepsy and its treatment
Abstract Seizures in some 30% to 40% of patients with epilepsy fail to respond to
antiepileptic drugs or other treatments. While much has been made of the risks of new drug …
antiepileptic drugs or other treatments. While much has been made of the risks of new drug …
Incidence and mechanisms of cardiorespiratory arrests in epilepsy monitoring units (MORTEMUS): a retrospective study
Background Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in
people with chronic refractory epilepsy. Very rarely, SUDEP occurs in epilepsy monitoring …
people with chronic refractory epilepsy. Very rarely, SUDEP occurs in epilepsy monitoring …
New avenues for anti-epileptic drug discovery and development
W Löscher, H Klitgaard, RE Twyman… - Nature reviews drug …, 2013 - nature.com
Despite the introduction of over 15 third-generation anti-epileptic drugs, current medications
fail to control seizures in 20–30% of patients. However, our understanding of the …
fail to control seizures in 20–30% of patients. However, our understanding of the …