A comprehensive review of recent advances in silk sericin: Extraction approaches, structure, biochemical characterization, and biomedical applications

M Saad, LM El-Samad, RA Gomaa… - International Journal of …, 2023 - Elsevier
Silks are natural polymers that have been widely used for centuries. Silk consists of a
filament core protein, termed fibroin, and a glue-like coating substance formed of sericin …

Diverse silk and silk-like proteins derived from terrestrial and marine organisms and their applications

D Jung, J Lee, TY Park, YJ Yang, HJ Cha - Acta Biomaterialia, 2021 - Elsevier
Organisms develop unique systems in a given environment. In the process of adaptation,
they employ materials in a clever way, which has inspired mankind extensively …

Evolution of sequence-diverse disordered regions in a protein family: order within the chaos

T Shafee, A Bacic, K Johnson - Molecular Biology and Evolution, 2020 - academic.oup.com
Approaches for studying the evolution of globular proteins are now well established yet are
unsuitable for disordered sequences. Our understanding of the evolution of proteins …

Mimicry of silk utilizing synthetic polypeptides

NJ Chan, S Lentz, PA Gurr, T Scheibel… - Progress in Polymer …, 2022 - Elsevier
For thousands of years,'silk'and silk-based materials have played an important role for
mankind. Today, silk-based materials increasingly find use in novel application areas such …

Rational design of new materials using recombinant structural proteins: Current state and future challenges

TD Sutherland, MG Huson, TD Rapson - Journal of structural biology, 2018 - Elsevier
Sequence-definable polymers are seen as a prerequisite for design of future materials, with
many polymer scientists regarding such polymers as the holy grail of polymer science …

[HTML][HTML] Micromolar biosensing of nitric oxide using myoglobin immobilized in a synthetic silk film

TD Rapson, JS Church, HE Trueman, H Dacres… - Biosensors and …, 2014 - Elsevier
In this work we investigate the use of coiled-coil silk proteins, produced in recombinant
Escherichia coli, as a new material for immobilizing biosensors. Myoglobin was embedded …

Production of recombinant coiled coil silk proteins for materials synthesis

PJ Shilling, L Pontes-Braz, L Mitchell, L Howell… - Protein Expression and …, 2025 - Elsevier
Rational design of fundamentally new advanced materials would be facilitated by availability
of polymers with controlled monomer sequence. Recombinant proteins offer polymers with …

Recombinant structural proteins and their use in future materials

TD Sutherland, TD Rapson, MG Huson… - … Proteins: Structures and …, 2017 - Springer
Recombinant proteins are polymers that offer the materials engineer absolute control over
chain length and composition: key attributes required for design of advanced polymeric …

Stabilization of viruses by encapsulation in silk proteins

TD Sutherland, A Sriskantha, JS Church… - … applied materials & …, 2014 - ACS Publications
Viruses are important for a range of modern day applications. However, their utility is limited
by their susceptibility to temperature degradation. In this study, we report a simple system to …

De novo engineering of solid-state metalloproteins using recombinant coiled-coil silk

TD Rapson, TD Sutherland, JS Church… - ACS Biomaterials …, 2015 - ACS Publications
To achieve the sophisticated chemistry required for life, nature uses metal containing
proteins (metalloproteins). However, despite intensive research efforts, very few of these …