PPAR-γ signaling in nonalcoholic fatty liver disease: Pathogenesis and therapeutic targets
H Chen, H Tan, J Wan, Y Zeng, J Wang… - Pharmacology & …, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), currently the leading cause of global chronic liver
disease, has emerged as a major public health problem, more efficient therapeutics of which …
disease, has emerged as a major public health problem, more efficient therapeutics of which …
The role of tumor necrosis factor-alpha in the pathogenesis and treatment of nonalcoholic fatty liver disease
ID Vachliotis, SA Polyzos - Current obesity reports, 2023 - Springer
Abstract Purpose of Review To summarize experimental and clinical evidence on the
association between tumor necrosis factor-α (TNF-α) and nonalcoholic fatty liver disease …
association between tumor necrosis factor-α (TNF-α) and nonalcoholic fatty liver disease …
Saroglitazar, a PPAR‐α/γ agonist, for treatment of NAFLD: a randomized controlled double‐blind phase 2 trial
S Gawrieh, M Noureddin, N Loo, R Mohseni… - …, 2021 - Wiley Online Library
Background and Aims NAFLD is characterized by insulin resistance and dysregulated lipid
and glucose metabolism. Saroglitazar, a dual peroxisome proliferator activated receptor‐α/γ …
and glucose metabolism. Saroglitazar, a dual peroxisome proliferator activated receptor‐α/γ …
Antioxidant peptides from monkfish swim bladders: ameliorating NAFLD in vitro by suppressing lipid accumulation and oxidative stress via regulating AMPK/Nrf2 …
MF Wu, QH **, Y Sheng, YM Wang, WY Wang, CF Chi… - Marine drugs, 2023 - mdpi.com
In this study, we investigate the ameliorating functions of QDYD (MSP2), ARW (MSP8),
DDGGK (MSP10), YPAGP (MSP13) and DPAGP (MSP18) from monkfish swim bladders on …
DDGGK (MSP10), YPAGP (MSP13) and DPAGP (MSP18) from monkfish swim bladders on …
[PDF][PDF] A systematic review of animal models of NAFLD finds high‐fat, high‐fructose diets most closely resemble human NAFLD
YR Im, H Hunter, D de Gracia Hahn, A Duret… - …, 2021 - Wiley Online Library
Background and Aims Animal models of human disease are a key component of
translational hepatology research, yet there is no consensus on which model is optimal for …
translational hepatology research, yet there is no consensus on which model is optimal for …
Retracted: M2 Macrophage–Derived Exosomes Facilitate HCC Metastasis by Transferring αMβ2 Integrin to Tumor Cells
J Wu, W Gao, Q Tang, Y Yu, W You, Z Wu, Y Fan… - …, 2021 - Wiley Online Library
Background and Aims The development and progression of hepatocellular carcinoma
(HCC) is dependent on its local microenvironment. Tumor‐associated macrophages (TAMs) …
(HCC) is dependent on its local microenvironment. Tumor‐associated macrophages (TAMs) …
Nuclear receptors linking metabolism, inflammation, and fibrosis in nonalcoholic fatty liver disease
T Puengel, H Liu, A Guillot, F Heymann… - International journal of …, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) and its progressive form nonalcoholic
steatohepatitis (NASH) comprise a spectrum of chronic liver diseases in the global …
steatohepatitis (NASH) comprise a spectrum of chronic liver diseases in the global …
[HTML][HTML] Peroxisome proliferator-activated receptors: A key link between lipid metabolism and cancer progression
Y Li, Y Pan, X Zhao, S Wu, F Li, Y Wang, B Liu… - Clinical Nutrition, 2024 - Elsevier
Lipids represent the essential components of membranes, serve as fuels for high-energy
processes, and play crucial roles in signaling and cellular function. One of the key hallmarks …
processes, and play crucial roles in signaling and cellular function. One of the key hallmarks …
Current options and future directions for NAFLD and NASH treatment
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, with a broad spectrum ranging from simple steatosis to advanced stage of …
worldwide, with a broad spectrum ranging from simple steatosis to advanced stage of …
The effects of probiotics on small intestinal microbiota composition, inflammatory cytokines and intestinal permeability in patients with non-alcoholic fatty liver disease
N Ayob, KN Muhammad Nawawi, MH Mohamad Nor… - Biomedicines, 2023 - mdpi.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) has soared globally. As our
understanding of the disease grows, the role of the gut-liver axis (GLA) in NAFLD …
understanding of the disease grows, the role of the gut-liver axis (GLA) in NAFLD …