Carbohydrate recognition is crucial for biological processes ranging from development to
immune system function to host–pathogen interactions. The proteins that bind glycans are …

The emergence of SARS-CoV-2 variants and drug-resistant mutants calls for additional oral
antivirals. The SARS-CoV-2 papain-like protease (PLpro) is a promising but challenging …

The study of protein-drug interaction plays a crucial role in understanding drug mechanisms,
identifying new drug targets and biomarkers, and facilitating drug development and disease …

Weak hydrogen bonds, such as OH··· π and CH··· O, are thought to direct biochemical
assembly, molecular recognition, and chemical selectivity but are seldom observed in …

Fibroins' transition from liquid to solid is fundamental to spinning and underpins the
impressive native properties of silk. Herein, we establish a fibroin heavy chain fold for the …

Single crystal X-ray diffraction is considered to be a highly reliable method for determining
the molecular structures and absolute conformation at the atomic level, but this technique is …

At the heart of drug design is the discovery of molecules that bind with high affinity to their
drug targets. Biotin forms the strongest known noncovalent ligand–protein interactions with …

Halogen bonding is increasingly utilized in efforts to achieve high affinity and selectivity of
molecules designed to bind proteins, making it paramount to understand the relationship …

A new family of luminescent heteroleptic Ru (II)-terpyridine complexes coupled with stilbene-
appended naphthalene, anthracene, and pyrene motifs is reported. Each of the complexes …

Background Chlorophenols are routinely determined in aquatic systems to check
compliance with the restrictive international legislations set for protection of human and …