Systematic evolution of ligands by exponential enrichment (SELEX) has been used to
discover thousands of aptamers since its development in 1990. Aptamers are short single …

Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Wearable technologies for personalized monitoring require sensors that track biomarkers
often present at low levels. Cortisol—a key stress biomarker—is present in sweat at low …

Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

L‐lactate is a key metabolite indicative of physiological states, glycolysis pathways, and
various diseases such as sepsis, heart attack, lactate acidosis, and cancer. Detection of …

Psychological stress is a major factor contributing to health discrepancies among
individuals. Sustained exposure to stress triggers signalling pathways in the brain, which …

Tetracyclines are a group of important antibiotics with a common four-ring scaffold. While
most tetracyclines are currently used only in animals, their leaching into the environment …

Aptamers are a promising class of affinity reagents because signal transduction
mechanisms can be built into the reagent, so that they can directly produce a physically …

Stress is part of everyone's life and is exacerbated by traumatic events such as pandemics,
disasters, violence, lifestyle changes, and health disorders. Chronic stress has many …