Human papilloma virus-associated cervical cancer and health disparities

P Olusola, HN Banerjee, JV Philley, S Dasgupta - Cells, 2019 - mdpi.com
Cervical cancer develops through persistent infection with high-risk human papilloma virus
(hrHPV) and is a leading cause of death among women worldwide and in the United States …

Mitochondria in health and disease

S Chakrabarty, SP Kabekkodu, RP Singh, K Thangaraj… - Mitochondrion, 2018 - Elsevier
Mitochondrial biology has become an area of intense research owing to the unique
physiology of the organelle and its role in several types of cancers and other disorders. It …

Association of mitochondrial DNA levels with frailty and all-cause mortality

FN Ashar, A Moes, AZ Moore, ML Grove… - Journal of molecular …, 2015 - Springer
Mitochondrial function is altered with age and variants in mitochondrial DNA (mtDNA)
modulate risk for several age-related disease states. However, the association of mtDNA …

[HTML][HTML] Association of particulate matter air pollution with leukocyte mitochondrial DNA copy number

X Wang, JE Hart, Q Liu, S Wu, H Nan, F Laden - Environment international, 2020 - Elsevier
Background Ambient particulate matter (PM) has been associated with mitochondrial
damage and dysfunction caused by excessive oxidative stress, but the associations …

Double C-2 like domain beta (DOC2B) induces calcium dependent oxidative stress to promote lipotoxicity and mitochondrial dysfunction for its tumor suppressive …

D Adiga, S Bhat, V Shukla, HV Shah… - Free Radical Biology …, 2023 - Elsevier
Mitochondria are biosynthetic and bioenergetic organelles that regulate many biological
processes, including metabolism, oxidative stress, and cell death. Cervical cancer (CC) cells …

Impact of bisphenol a on structure and function of mitochondria: a critical review

D Nayak, D Adiga, NG Khan, PS Rai… - Reviews of …, 2022 - Springer
Bisphenol A (BPA) is an industrial chemical used extensively to manufacture polycarbonate
plastics and epoxy resins. Because of its estrogen-mimicking properties, BPA acts as an …

Mitochondrial DNA genomes revealed different patterns of high-altitude adaptation in high-altitude Tajiks compared with Tibetans and Sherpas

Y Chen, L Gong, X Liu, X Chen, S Yang, Y Luo - Scientific Reports, 2020 - nature.com
Abstract High-altitude Tajiks (HA-Tajiks), Tibetans and Sherpas are three groups of high-
altitude native people in China. The differences in the mtDNA genome between the three …

Esophageal squamous cell carcinoma with low mitochondrial copy number has mesenchymal and stem-like characteristics, and contributes to poor prognosis

Y Masuike, K Tanaka, T Makino, M Yamasaki… - PLoS …, 2018 - journals.plos.org
Alterations in mitochondrial DNA (mtDNA) copy numbers in various human cancers have
been studied, but any such changes in esophageal squamous cell carcinoma (ESCC) are …

Altered mitochondrial DNA copy number in cervical exfoliated cells among high‑risk HPV‑positive and HPV‑negative women

R Al-Awadhi, M Alroomy… - Experimental and …, 2023 - spandidos-publications.com
The majority of cervical cancer cases are due to human papillomavirus (HPV) infection.
However, certain cases of cervical cancer are not caused by HPV. Recent studies have …

Design and synthesis of novel reactive oxygen species inducers for the treatment of pancreatic ductal adenocarcinoma

Y Kuang, M Sechi, S Nurra, M Ljungman… - Journal of medicinal …, 2018 - ACS Publications
Altering redox homeostasis provides distinctive therapeutic opportunities for the treatment of
pancreatic cancer. Quinazolinediones (QDs) are novel redox modulators that we previously …