Long-chain polyunsaturated fatty acids (LC-PUFA) are major components of complex lipid
molecules and are also involved in numerous critical biological processes. Studies …

The Genome 10K Project was established in 2009 by a consortium of biologists and
genome scientists determined to facilitate the sequencing and analysis of the complete …

We investigated genome folding across the eukaryotic tree of life. We find two types of three-
dimensional (3D) genome architectures at the chromosome scale. Each type appears and …

Although it is widely believed that early vertebrate evolution was shaped by ancient whole-
genome duplications, the number, timing and mechanism of these events remain elusive …

Ancient polyploidization events have had a lasting impact on vertebrate genome structure,
organization and function. Some key questions regarding the number of ancient …

The sea lamprey (Petromyzon marinus) serves as a comparative model for reconstructing
vertebrate evolution. To enable more informed analyses, we developed a new assembly of …

As the only surviving lineages of jawless fishes, hagfishes and lampreys provide a crucial
window into early vertebrate evolution,–. Here we investigate the complex history, timing …

The origin of vertebrates was accompanied by the advent of a novel cell type: the neural
crest. Emerging from the central nervous system, these cells migrate to diverse locations and …

Background The functional divergence of duplicate genes (ohnologues) retained from whole
genome duplication (WGD) is thought to promote evolutionary diversification. However …

The aryl hydrocarbon receptor (AHR) was for many years of interest only to pharmacologists
and toxicologists. However, this protein has fundamental roles in biology that are being …