Robustness is a ubiquitously observed property of biological systems. It is considered to be
a fundamental feature of complex evolvable systems. It is attained by several underlying …

Robustness, the ability to maintain performance in the face of perturbations and uncertainty,
is a long-recognized key property of living systems. Owing to intimate links to cellular …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Vehicular Ad hoc NETworks (VANETs) play a key role in the design and development of
Intelligent Transportation Systems (ITS) that aim to improve road safety and transportation …

Biochemical systems theory (BST) is the foundation for a set of analytical andmodeling tools
that facilitate the analysis of dynamic biological systems. This paper depicts major …

Like engineering systems, biological systems must also operate effectively in the presence
of internal and external uncertainty—such as genetic mutations or temperature changes, for …

Metabolic pathways in cells must be sufficiently robust to tolerate fluctuations in expression
levels and changes in environmental conditions. Perturbations in expression levels may …

Taking ideas from nature has been a theme of humanity's technological progress but it is
only our newfound expertise in molecular manipulation and complex nonlinear dynamics …

The newly emerging field of systems biology involves a judicious interplay between high‐
throughput 'wet'experimentation, computational modelling and technology development …

Background A biological system's robustness to mutations and its evolution are influenced
by the structure of its viable space, the region of its space of biochemical parameters where …