microRNA as a therapeutic for ischemic stroke
R Todoran, SR Falcione, M Clarke, T Joy… - Neurochemistry …, 2023 - Elsevier
Abstract microRNA (miRNA) are important regulators of gene expression. miRNA have the
potential as a treatment to modulate genes, pathways and cells involved in ischemic stroke …
potential as a treatment to modulate genes, pathways and cells involved in ischemic stroke …
An overview of the cytoskeleton-associated role of PDLIM5
X Huang, R Qu, J Ouyang, S Zhong, J Dai - Frontiers in Physiology, 2020 - frontiersin.org
Regenerative medicine represented by stem cell technology has become one of the pillar
medical technologies for human disease treatment. Cytoskeleton plays important roles in …
medical technologies for human disease treatment. Cytoskeleton plays important roles in …
[HTML][HTML] The molecular mechanism of LRP1 in physiological vascular homeostasis and signal transduction pathways
Z He, G Wang, J Wu, Z Tang, M Luo - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Interactions between vascular smooth muscle cells (VSMCs), endothelial cells (ECs),
pericytes (PCs) and macrophages (MФ), the major components of blood vessels, play a …
pericytes (PCs) and macrophages (MФ), the major components of blood vessels, play a …
TMAO upregulates members of the miR-17/92 cluster and impacts targets associated with atherosclerosis
L Díez-Ricote, P Ruiz-Valderrey, V Micó… - International Journal of …, 2022 - mdpi.com
Atherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its
onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, with a …
onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, with a …
Non-coding RNA networks in pulmonary hypertension
H Zang, Q Zhang, X Li - Frontiers in Genetics, 2021 - frontiersin.org
Non-coding RNAs (ncRNAs) are involved in various cellular processes. There are several
ncRNA classes, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and …
ncRNA classes, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and …
LncRNA CASC2 inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation and migration by regulating the miR-222/ING5 axis
Y Han, Y Liu, C Yang, C Gao, X Guo… - Cellular & molecular …, 2020 - Springer
Background Pulmonary arterial hypertension (PAH) is often characterized by cell
proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs). LncRNA …
proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs). LncRNA …
Cellular mechanosignaling in pulmonary arterial hypertension
A Wang, D Valdez-Jasso - Biophysical reviews, 2021 - Springer
Pulmonary arterial hypertension (PAH) is a vasculopathy characterized by sustained
elevated pulmonary arterial pressures in which the pulmonary vasculature undergoes …
elevated pulmonary arterial pressures in which the pulmonary vasculature undergoes …
Human umbilical cord mesenchymal stem cell-derived exosomal microRNA-148a-3p inhibits neointimal hyperplasia by targeting Serpine1
X Zhang, Y Zhou, Y Ye, R Wu, W Li, C Yao… - Archives of Biochemistry …, 2022 - Elsevier
Background Restenosis is inevitable when patients undergo percutaneous transluminal
angioplasty due to neointimal hyperplasia (NIH). Human umbilical cord mesenchymal stem …
angioplasty due to neointimal hyperplasia (NIH). Human umbilical cord mesenchymal stem …
miR-19 targets PTEN and mediates high mobility group protein B1 (HMGB1)-induced proliferation and migration of human airway smooth muscle cells
C Hou, Y Chen, X Huang, Q Huang, M Li, X Tan - PLoS One, 2019 - journals.plos.org
Background The abnormal proliferation and migration of airway smooth muscle (ASM) cells
contributes to airway remodeling during asthma. MiR-19a has been demonstrated to …
contributes to airway remodeling during asthma. MiR-19a has been demonstrated to …
An overview of miRNAs involved in PASMC phenotypic switching in pulmonary hypertension
W Zhang, Z Tao, F Xu, Q Diao, J Li… - BioMed Research …, 2021 - Wiley Online Library
Pulmonary hypertension (PH) is occult, with no distinctive clinical manifestations and a poor
prognosis. Pulmonary vascular remodelling is an important pathological feature in which …
prognosis. Pulmonary vascular remodelling is an important pathological feature in which …