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Molecular mechanisms linking oxidative stress and diabetes mellitus
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …
Obesity and dyslipidemia
J Vekic, A Zeljkovic, A Stefanovic, Z Jelic-Ivanovic… - Metabolism, 2019 - Elsevier
Obesity, a pandemic of the modern world, is intimately associated with dyslipidemia, which
is mainly driven by the effects of insulin resistance and pro-inflammatory adipokines …
is mainly driven by the effects of insulin resistance and pro-inflammatory adipokines …
A review of the molecular mechanisms of hyperglycemia‐induced free radical generation leading to oxidative stress
The prevalence of diabetes is growing worldwide with an increasing morbidity and mortality
associated with the development of diabetes complications. Free radical production is a …
associated with the development of diabetes complications. Free radical production is a …
The therapeutic and diagnostic role of exosomes in cardiovascular diseases
Exosomes are nano-sized membranous vesicles that are secreted by cells. They have an
important role in transferring proteins, mRNA, miRNA and other bioactive molecules …
important role in transferring proteins, mRNA, miRNA and other bioactive molecules …
Unlocking the full potential of SGLT2 inhibitors: expanding applications beyond glycemic control
The number of diabetic patients has risen dramatically in recent decades, owing mostly to
the rising incidence of type 2 diabetes mellitus (T2DM). Several oral antidiabetic …
the rising incidence of type 2 diabetes mellitus (T2DM). Several oral antidiabetic …
Differential expression of urinary exosomal microRNAs miR-21-5p and miR-30b-5p in individuals with diabetic kidney disease
J Zang, AP Maxwell, DA Simpson, GJ McKay - Scientific Reports, 2019 - nature.com
Biomarkers for the identification of diabetic kidney disease (DKD) are needed as current
tests lack sensitivity for detecting early kidney damage. MicroRNAs (miRNAs) are short, non …
tests lack sensitivity for detecting early kidney damage. MicroRNAs (miRNAs) are short, non …
Association between passive smoking and cardiovascular disease: A systematic review and meta‐analysis
Background The association between passive smoking (PS) and cardiovascular disease
(CVD) has not yet been fully clarified. Objective This meta‐analysis was performed to …
(CVD) has not yet been fully clarified. Objective This meta‐analysis was performed to …
Mitochondrial dysfunction in cardiovascular disease: Current status of translational research/clinical and therapeutic implications
AS Manolis, AA Manolis, TA Manolis… - Medicinal Research …, 2021 - Wiley Online Library
Mitochondria provide energy to the cell during aerobic respiration by supplying~ 95% of the
adenosine triphosphate (ATP) molecules via oxidative phosphorylation. These organelles …
adenosine triphosphate (ATP) molecules via oxidative phosphorylation. These organelles …
Oxidative stress signaling in the pathogenesis of diabetic cardiomyopathy and the potential therapeutic role of antioxidant naringenin
N Xu, S Liu, Y Zhang, Y Chen, Y Zuo, X Tan, B Liao… - Redox …, 2023 - Taylor & Francis
Diabetes mellitus (DM) is one of the most prevalent metabolic disorders that poses a global
threat to human health. It can lead to complications in multiple organs and tissues, owing to …
threat to human health. It can lead to complications in multiple organs and tissues, owing to …
Molecular mechanisms by which aerobic exercise induces insulin sensitivity
Insulin resistance is a key feature of Type 2 diabetes and an important therapeutic target to
address glycemic control to prevent diabetic complications. Lifestyle advice is the first step in …
address glycemic control to prevent diabetic complications. Lifestyle advice is the first step in …