The structure of molecules, particularly the dynamic changes in structure, plays an essential
role in understanding physical and chemical phenomena. Time-resolved (TR) scattering …

Serial crystallography, born from groundbreaking experiments at the Linac Coherent Light
Source in 2009, has evolved into a pivotal technique in structural biology. Initially pioneered …

High-intensity femtosecond pulses from an X-ray free-electron laser enable pump–probe
experiments for the investigation of electronic and nuclear changes during light-induced …

Cryptochromes (CRYs) are blue-light receptors that regulate diverse aspects of plant growth.
However, whether and how non-photoexcited CRYs function in darkness or non-blue-light …

Over the last decade, the development of time-resolved serial crystallography (TR-SX) at X-
ray free-electron lasers (XFELs) and synchrotrons has allowed researchers to study …

Macromolecular crystallography has historically provided the atomic structures of proteins
fundamental to cellular functions. However, the advent of cryo-electron microscopy for …

This study presents the polarizable quantum mechanics/molecular mechanics (QM/MM)
embedding of the state-averaged complete active space self-consistent field (SA-CASSCF) …

Flavin adenine dinucleotide (FAD), serving as a light-absorbing coenzyme factor, can
undergo conformationally isomeric complexation within different enzymes to form various …

Understanding protein function would be facilitated by direct, real-time observation of
chemical kinetics in the atomic structure. The selectivity filter (SF) of the K+ channel provides …

We provide an experimentalist's perspective on the present state-of-the-art in the studies of
low-energy electron interactions with common radiosensitizers, including compounds used …