The global burden of SLE: prevalence, health disparities and socioeconomic impact
EE Carter, SG Barr, AE Clarke - Nature reviews rheumatology, 2016 - nature.com
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can
potentially lead to serious organ complications and even death. Its global burden—in terms …
potentially lead to serious organ complications and even death. Its global burden—in terms …
Systematic review of the epidemiology of systemic lupus erythematosus in the Asia‐Pacific region: prevalence, incidence, clinical features, and mortality
RW Jakes, SC Bae, W Louthrenoo… - Arthritis care & …, 2012 - Wiley Online Library
Objective Systemic lupus erythematosus (SLE), a chronic multisystem autoimmune disease
with a wide spectrum of manifestations, shows considerable variation across the globe …
with a wide spectrum of manifestations, shows considerable variation across the globe …
A phase III, randomized, placebo‐controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus …
R Furie, M Petri, O Zamani, R Cervera… - Arthritis & …, 2011 - Wiley Online Library
Objective To assess the efficacy/safety of the B lymphocyte stimulator inhibitor belimumab
plus standard therapy compared with placebo plus standard therapy in active systemic lupus …
plus standard therapy compared with placebo plus standard therapy in active systemic lupus …
Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial
SV Navarra, RM Guzmán, AE Gallacher, S Hall… - The Lancet, 2011 - thelancet.com
Background Systemic lupus erythematosus is a heterogeneous autoimmune disease that is
associated with B-cell hyperactivity, autoantibodies, and increased concentrations of B …
associated with B-cell hyperactivity, autoantibodies, and increased concentrations of B …
N‐acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: A randomized, double …
ZW Lai, R Hanczko, E Bonilla, TN Caza… - Arthritis & …, 2012 - Wiley Online Library
Objective Systemic lupus erythematosus (SLE) patients exhibit T cell dysfunction, which can
be regulated through mitochondrial transmembrane potential (Δψm) and mammalian target …
be regulated through mitochondrial transmembrane potential (Δψm) and mammalian target …
Anifrolumab reduces flare rates in patients with moderate to severe systemic lupus erythematosus
Background Systemic lupus erythematosus (SLE) management objectives include
preventing disease flares while minimizing glucocorticoid exposure. Pooled data from the …
preventing disease flares while minimizing glucocorticoid exposure. Pooled data from the …
Baseline predictors of systemic lupus erythematosus flares: data from the combined placebo groups in the phase III belimumab trials
MA Petri, RF Van Vollenhoven, J Buyon… - Arthritis & …, 2013 - Wiley Online Library
Objective To identify predictors of moderate‐to‐severe systemic lupus erythematosus (SLE)
flare in 562 patients treated with standard therapy alone in phase III belimumab trials, and to …
flare in 562 patients treated with standard therapy alone in phase III belimumab trials, and to …
The number of flares patients experience impacts on damage accrual in systemic lupus erythematosus: data from a multiethnic Latin American cohort
Purpose To determine the association between the number of flares systemic lupus
erythematosus (SLE) patients experience and damage accrual, independently of other …
erythematosus (SLE) patients experience and damage accrual, independently of other …
Healthcare utilization and cost of systemic lupus erythematosus in a US managed care health plan
C Garris, P Jhingran, D Bass… - Journal of medical …, 2013 - Taylor & Francis
Objective: To assess healthcare resource utilization and costs in a cohort of US managed
care patients with systemic lupus erythematosus (SLE). Methods: Claims data from a large …
care patients with systemic lupus erythematosus (SLE). Methods: Claims data from a large …
Predictive biological markers of systemic lupus erythematosus flares: a systematic literature review
N Gensous, A Marti, T Barnetche, P Blanco… - Arthritis research & …, 2017 - Springer
Background The aim of this study was to identify the most reliable biomarkers in the
literature that could be used as flare predictors in systemic lupus erythematosus (SLE) …
literature that could be used as flare predictors in systemic lupus erythematosus (SLE) …