Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Cell-based and stem-cell-based treatments for spinal cord injury: evidence from clinical trials
Spinal cord injury is a severely disabling neurological condition leading to impaired mobility,
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
Progression in translational research on spinal cord injury based on microenvironment imbalance
B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …
and imposes a considerable burden on patients, families, and society. Repair of the injured …
The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration
Over the past decade, we have witnessed a flourishing of novel strategies to enhance
neuroplasticity and promote axon regeneration following spinal cord injury, and results from …
neuroplasticity and promote axon regeneration following spinal cord injury, and results from …
The dialogue between neuroinflammation and adult neurogenesis: mechanisms involved and alterations in neurological diseases
Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …
First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol
K Sugai, M Sumida, T Shofuda, R Yamaguchi… - Regenerative …, 2021 - Elsevier
Introduction Our group has conducted extensive basic and preclinical studies of the use of
human induced pluripotent cell (iPSC)-derived neural stem/progenitor cell (hiPSC-NS/PC) …
human induced pluripotent cell (iPSC)-derived neural stem/progenitor cell (hiPSC-NS/PC) …
Acute spinal cord injury: Pathophysiology and pharmacological intervention
Y Zhang, A Al Mamun, Y Yuan… - Molecular …, 2021 - spandidos-publications.com
Spinal cord injury (SCI) is one of the most debilitating of all the traumatic conditions that
afflict individuals. For a number of years, extensive studies have been conducted to clarify …
afflict individuals. For a number of years, extensive studies have been conducted to clarify …
Supramolecular hydrogel microspheres of platelet-derived growth factor mimetic peptide promote recovery from spinal cord injury
W Wu, S Jia, H Xu, Z Gao, Z Wang, B Lu, Y Ai, Y Liu… - ACS …, 2023 - ACS Publications
Neural stem cells (NSCs) are considered to be prospective replacements for neuronal cell
loss as a result of spinal cord injury (SCI). However, the survival and neuronal differentiation …
loss as a result of spinal cord injury (SCI). However, the survival and neuronal differentiation …
Progress in stem cell therapy for spinal cord injury
L Gao, Y Peng, W Xu, P He, T Li, X Lu… - Stem Cells …, 2020 - Wiley Online Library
Background. Spinal cord injury (SCI) is one of the serious neurological diseases that occur
in young people with high morbidity and disability. However, there is still a lack of effective …
in young people with high morbidity and disability. However, there is still a lack of effective …
Regenerative therapies for spinal cord injury
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …
adults at its onset. To date, no effective regenerative treatment has been developed. Over …