SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms

FJ Pardo-Palacios, A Arzalluz-Luque, L Kondratova… - Nature …, 2024 - nature.com
SQANTI3 is a tool designed for the quality control, curation and annotation of long-read
transcript models obtained with third-generation sequencing technologies. Leveraging its …

De novo basecalling of m6A modifications at single molecule and single nucleotide resolution

S Cruciani, A Delgado-Tejedor, LP Pryszcz, R Medina… - Biorxiv, 2023 - biorxiv.org
ABSTRACT RNA modifications hold pivotal roles in sha** the fate and function of RNA
molecules. Although nanopore sequencing technologies have proven successful at …

Nano-DMS-MaP-seq allows isoform specific RNA structure determination

R Smyth, P Bohn, AS Gribling-Burrer, U Ambi - 2022 - researchsquare.com
Chemical probing experiments interrogate RNA structure by reacting with unpaired residues
whose positions are typically read out by mutational profiling on short-read sequencing …