The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

Glycosphingolipids (GSL s) comprise a heterogeneous group of membrane lipids formed by
a ceramide backbone covalently linked to a glycan moiety. Hundreds of different glycans …

Glycosylation is a very frequent and functionally important post-translational protein
modification that undergoes profound changes in cancer. Growth and death factor receptors …

Epithelial‐mesenchymal transition (EMT) is pivotal in the initiation and development of
cancer cell metastasis. We observed that the abundance of glycosphingolipids (GSLs) …

The intricate cellular process, known as the epithelial-mesenchymal transition (EMT),
significantly influences solid tumors development. Changes in cell shape, metabolism, and …

Gangliosides, the glycosphingolipids carrying one or several sialic acid residues, are mostly
localized at the plasma membrane in lipid raft domains and implicated in many cellular …

Lipids are the key component of all membranes composed of a variety of molecules that
transduce intracellular signaling and provide energy to the cells in the absence of nutrients …

Glycosylation is a common posttranslational modification on membrane-associated and
secreted proteins that is of pivotal importance for regulating cell functions. Aberrant …

Every living cell is covered with a dense and complex layer of glycans on the cell surface,
which have important functions in the interaction between cells and their environment …

Aberrant expression of glycosphingolipids (GSLs) is a unique feature of cancer and stromal
cells in tumor microenvironments. Although the impact of GSLs on tumor progression …