The role of microRNAs in the gastric cancer tumor microenvironment

X Yu, Y Zhang, F Luo, Q Zhou, L Zhu - Molecular Cancer, 2024 - Springer
Background Gastric cancer (GC) is one of the deadliest malignant tumors with unknown
pathogenesis. Due to its treatment resistance, high recurrence rate, and lack of reliable early …

Exosomes in the tumor microenvironment of sarcoma: from biological functions to clinical applications

H Ye, X Hu, Y Wen, C Tu, F Hornicek, Z Duan… - Journal of …, 2022 - Springer
The current diagnosis and treatment of sarcoma continue to show limited timeliness and
efficacy. In order to enable the early detection and management of sarcoma, increasing …

Prognostic value of soluble PD-L1 and exosomal PD-L1 in advanced gastric cancer patients receiving systemic chemotherapy

K Shin, J Kim, SJ Park, MA Lee, JM Park, MG Choi… - Scientific Reports, 2023 - nature.com
The prognostic role of soluble PD-L1 (sPD-L1) and exosomal PD-L1 (exoPD-L1) in patients
with gastric cancer (GC) receiving systemic chemotherapy remains unelucidated. Thus, we …

Single-cell analysis in immuno-oncology

MI Christodoulou, A Zaravinos - International Journal of Molecular …, 2023 - mdpi.com
The complexity of the cellular and non-cellular milieu surrounding human tumors plays a
decisive role in the course and outcome of disease. The high variability in the distribution of …

Advances in immunotherapy for breast cancer and feline mammary carcinoma: From molecular basis to novel therapeutic targets

T Vilela, S Valente, J Correia, F Ferreira - Biochimica et Biophysica Acta …, 2024 - Elsevier
The role of inflammation in cancer is a topic that has been investigated for many years. As
established, inflammation emerges as a defining characteristic of cancer, presenting itself as …

The landscape of tumor-infiltrating immune cells in feline mammary carcinoma: pathological and clinical implications

C Nascimento, A Gameiro, J Correia, J Ferreira… - Cells, 2022 - mdpi.com
Feline mammary carcinoma (FMC) shares key molecular and clinicopathological features
with human breast cancer. We have herein studied the inflammatory infiltrate of FMC in …

Nano-baicalein facilitates chemotherapy in breast cancer by targeting tumor microenvironment

F Zheng, Y Luo, Y Liu, Y Gao, W Chen, K Wei - International Journal of …, 2023 - Elsevier
Cancer-associated fibroblasts constitute a significant component in the tumor
microenvironment, playing a pivotal role in tumor proliferation, invasion, migration, and …

[HTML][HTML] Towards dual function of autophagy in breast cancer: A potent regulator of tumor progression and therapy response

M Hashemi, MDA Paskeh, S Orouei, P Abbasi… - Biomedicine & …, 2023 - Elsevier
As a devastating disease, breast cancer has been responsible for decrease in life
expectancy of females and its morbidity and mortality are high. Breast cancer is the most …

TGF-β and TNF-α interaction promotes the expression of MMP-9 through H3K36 dimethylation: implications in breast cancer metastasis

S Kochumon, A Al-Sayyar, T Jacob, F Bahman… - Frontiers in …, 2024 - frontiersin.org
Increased MMP-9 expression in the tumor microenvironment (TME) plays a crucial role in
the extracellular matrix remodeling to facilitate cancer invasion and metastasis. However …

[HTML][HTML] Oncolytic virus-based combination therapy in breast cancer

A Bahreyni, Y Mohamud, H Luo - Cancer Letters, 2024 - Elsevier
Breast cancer continues to pose significant challenges in the field of oncology, necessitating
innovative treatment approaches. Among these, oncolytic viruses have emerged as a …