Emerging evidence for functional peptides encoded by short open reading frames

SJ Andrews, JA Rothnagel - Nature Reviews Genetics, 2014 - nature.com
Short open reading frames (sORFs) are a common feature of all genomes, but their coding
potential has mostly been disregarded, partly because of the difficulty in determining …

BIOPEP database and other programs for processing bioactive peptide sequences

P Minkiewicz, J Dziuba, A Iwaniak… - Journal of AOAC …, 2008 - academic.oup.com
This review presents the potential for application of computational tools in peptide science
based on a sample BIOPEP database and program as well as other programs and …

Extensive translation of small open reading frames revealed by Poly-Ribo-Seq

JL Aspden, YC Eyre-Walker, RJ Phillips, U Amin… - elife, 2014 - elifesciences.org
Thousands of small Open Reading Frames (smORFs) with the potential to encode small
peptides of fewer than 100 amino acids exist in our genomes. However, the number of …

Peptidomics: A review of clinical applications and methodologies

RE Foreman, AL George, F Reimann… - Journal of Proteome …, 2021 - ACS Publications
Improvements in both liquid chromatography (LC) and mass spectrometry (MS)
instrumentation have greatly enhanced proteomic and small molecule metabolomic analysis …

Current peptidomics: applications, purification, identification, quantification, and functional analysis

DC Dallas, A Guerrero, EA Parker, RC Robinson… - …, 2015 - Wiley Online Library
Peptidomics is an emerging field branching from proteomics that targets endogenously
produced protein fragments. Endogenous peptides are often functional within the body …

Combining mass spectrometry and machine learning to discover bioactive peptides

CT Madsen, JC Refsgaard, FG Teufel… - Nature …, 2022 - nature.com
Peptides play important roles in regulating biological processes and form the basis of a
multiplicity of therapeutic drugs. To date, only about 300 peptides in human have confirmed …

Techniques, perspectives, and challenges of bioactive peptide generation: A comprehensive systematic review

M Barati, F Javanmardi… - … Reviews in Food …, 2020 - Wiley Online Library
Due to the digestible refractory and absorbable structures of bioactive peptides (BPs), they
could induce notable biological impacts on the living organism. In this regard, the current …

Use of proteomics and peptidomics methods in food bioactive peptide science and engineering

J Carrasco-Castilla, AJ Hernández-Álvarez… - Food Engineering …, 2012 - Springer
Proteomic and peptidomic studies are emerging as an important part of the holistic approach
to food science and technology and have been recently applied in the study and production …

New developments and applications of bacteriocins and peptides in foods

S Mills, C Stanton, C Hill, RP Ross - Annual Review of Food …, 2011 - annualreviews.org
There is an increased desire for sophisticated foods, whereby consumers harbor higher
expectations of health-promoting benefits above basic nutrition. Moreover, there is a move …

NeuroPep: a comprehensive resource of neuropeptides

Y Wang, M Wang, S Yin, R Jang, J Wang, Z Xue… - Database, 2015 - academic.oup.com
Neuropeptides play a variety of roles in many physiological processes and serve as
potential therapeutic targets for the treatment of some nervous-system disorders. In recent …