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[HTML][HTML] Emerging roles of astrocyte Kir4. 1 channels in the pathogenesis and treatment of brain diseases
Y Ohno, N Kunisawa, S Shimizu - International Journal of Molecular …, 2021 - mdpi.com
Inwardly rectifying Kir4. 1 channels in astrocytes mediate spatial potassium (K+) buffering, a
clearance mechanism for excessive extracellular K+, in tripartite synapses. In addition to K+ …
clearance mechanism for excessive extracellular K+, in tripartite synapses. In addition to K+ …
Врожденный иммунитет при коронавирусной инфекции
Коронавирусы (CoV) представляют собой полиморфную группу респираторных
вирусов, вызывающих острые воспалительные заболевания у домашних и …
вирусов, вызывающих острые воспалительные заболевания у домашних и …
Inwardly rectifying potassium channel Kir4. 1 as a novel modulator of BDNF expression in astrocytes
Brain-derived neurotrophic factor (BDNF) is a key molecule essential for neural plasticity
and development, and is implicated in the pathophysiology of various central nervous …
and development, and is implicated in the pathophysiology of various central nervous …
Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain
YY Zhang, F Liu, ZH Fang, YL Li, HL Liao… - Brain, behavior, and …, 2022 - Elsevier
The spinal N-methyl-d-aspartate receptor (NMDAR), particularly their subtypes NR2A and
NR2B, plays pivotal roles in neuropathic and inflammatory pain. However, the roles of NR2A …
NR2B, plays pivotal roles in neuropathic and inflammatory pain. However, the roles of NR2A …
Role of astrocytic inwardly rectifying potassium (Kir) 4.1 channels in epileptogenesis
Astrocytes regulate potassium and glutamate homeostasis via inwardly rectifying potassium
(Kir) 4.1 channels in synapses, maintaining normal neural excitability. Numerous studies …
(Kir) 4.1 channels in synapses, maintaining normal neural excitability. Numerous studies …
Kir channel molecular physiology, pharmacology, and therapeutic implications
For the past two decades several scholarly reviews have appeared on the inwardly rectifying
potassium (Kir) channels. We would like to highlight two efforts in particular, which have …
potassium (Kir) channels. We would like to highlight two efforts in particular, which have …
Discovery, characterization, and effects on renal fluid and electrolyte excretion of the Kir4. 1 potassium channel pore blocker, VU0134992
The inward rectifier potassium (Kir) channel Kir4. 1 (KCNJ10) carries out important
physiologic roles in epithelial cells of the kidney, astrocytes in the central nervous system …
physiologic roles in epithelial cells of the kidney, astrocytes in the central nervous system …
[HTML][HTML] Innate immunity in coronavirus infection
VS Smirnov, AA Totolyan - Russian journal of infection and immunity, 2020 - iimmun.ru
Coronaviruses (CoVs) comprise a polymorphic group of respiratory viruses causing acute
inflammatory diseases in domestic and agricultural animals (chicken, pig, buffalo, cat, dog) …
inflammatory diseases in domestic and agricultural animals (chicken, pig, buffalo, cat, dog) …
VU6036720: the first potent and selective in vitro inhibitor of heteromeric Kir4. 1/5.1 inward rectifier potassium channels
ABSTRACT Heteromeric Kir4. 1/Kir5. 1 (KCNJ10/KCNJ16) inward rectifier potassium (Kir)
channels play key roles in the brain and kidney, but pharmacological tools for probing their …
channels play key roles in the brain and kidney, but pharmacological tools for probing their …
In vitro and in silico characterization of the inhibition of Kir4.1 channels by aminoglycoside antibiotics
R Morán‐Zendejas… - British Journal of …, 2020 - Wiley Online Library
Background and Purpose Aminoglycoside antibiotics are positively charged molecules that
are known to inhibit several ion channels. In this study, we have shown that …
are known to inhibit several ion channels. In this study, we have shown that …