Characteristics of early-onset vs late-onset colorectal cancer: a review

R Collaborative, AM Zaborowski, A Abdile… - JAMA …, 2021 - jamanetwork.com
Importance The incidence of early-onset colorectal cancer (younger than 50 years) is rising
globally, the reasons for which are unclear. It appears to represent a unique disease …

Urogenital function following robotic and laparoscopic rectal cancer surgery: meta-analysis

CA Fleming, C Cullinane, N Lynch… - British Journal of …, 2021 - academic.oup.com
Background Mixed results are reported on clinical and cancer outcomes in laparoscopic
rectal cancer surgery (LRCS) compared with robotic rectal cancer surgery (RRCS) …

[HTML][HTML] Delphi initiative for early-onset colorectal cancer (DIRECt) international management guidelines

GM Cavestro, A Mannucci, F Balaguer… - Clinical …, 2023 - Elsevier
Background & Aims Patients with early-onset colorectal cancer (eoCRC) are managed
according to guidelines that are not age-specific. A multidisciplinary international group …

Short-course radiotherapy with consolidation chemotherapy versus conventionally fractionated long-course chemoradiotherapy for locally advanced rectal cancer …

D Chakrabarti, S Rajan, N Akhtar… - British Journal of …, 2021 - academic.oup.com
Background The trial hypothesis was that, in a resource-constrained situation, short-course
radiotherapy would improve treatment compliance compared with conventional …

Early-onset colorectal cancer

V Nfonsam, E Wusterbarth, A Gong, P Vij - Surgical Oncology Clinics of …, 2022 - Elsevier
Colorectal cancer (CRC) is the third most common cancer in the world and is a leading
cause of morbidity and mortality. 1 In the United States, it is associated with the third highest …

Early-onset pancreatic cancer: clinical characteristics and survival outcomes

T Takeda, T Sasaki, Y Inoue, T Okamoto, C Mori, T Mie… - Pancreatology, 2022 - Elsevier
Background Early-onset pancreatic cancer (≤ 50 years, EOPC) is uncommon. This study
aims to characterize the clinical and survival characteristics of EOPC in comparison to late …

Different oncologic outcomes in early-onset and late-onset sporadic colorectal cancer: A regression analysis on 2073 patients

C Foppa, A Maroli, S Lauricella, A Luberto, C La Raja… - Cancers, 2022 - mdpi.com
Simple Summary Early-onset colorectal cancer (EOCRC) is on the rise. Reasons are
unknown and comparative results about long-term survival are still widely debated. This …

Age and metastasis–how age influences metastatic spread in cancer. Colorectal cancer as a model

E Pretzsch, H Nieß, F Bösch, CB Westphalen… - Cancer …, 2022 - Elsevier
Metastasis is the major cause of death in cancer patients. Whereas colorectal cancer (CRC)
incidence increases with age, metastatic spread seems to decline. Furthermore, the …

Watch and wait after a clinical complete response in rectal cancer patients younger than 50 years

RR Bahadoer, KCMJ Peeters, GL Beets… - British Journal of …, 2022 - academic.oup.com
Background Young-onset rectal cancer, in patients less than 50 years, is expected to
increase in the coming years. A watch-and-wait strategy is nowadays increasingly practised …

Early age of onset is an independent predictor for worse disease-free survival in sporadic rectal cancer patients. A comparative analysis of 980 consecutive patients

C Foppa, S Tamburello, A Maroli, M Carvello… - European Journal of …, 2022 - Elsevier
Background while interest on early-onset colorectal cancer (age≤ 49) is on the rise, studies
on early-onset rectal cancer (EORC) are limited. The aim of this study was to compare …