Sexually transmitted infections: challenges ahead

M Unemo, CS Bradshaw, JS Hocking… - The Lancet infectious …, 2017 - thelancet.com
WHO estimated that nearly 1 million people become infected every day with any of four
curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and …

Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future

M Unemo, WM Shafer - Clinical microbiology reviews, 2014 - Am Soc Microbiol
Neisseria gonorrhoeae is evolving into a superbug with resistance to previously and
currently recommended antimicrobials for treatment of gonorrhea, which is a major public …

Antimicrobial resistance in Neisseria gonorrhoeae: Global surveillance and a call for international collaborative action

T Wi, MM Lahra, F Ndowa, M Bala, JAR Dillon… - PLoS …, 2017 - journals.plos.org
Antimicrobial resistance in Neisseria gonorrhoeae: Global surveillance and a call for
international collaborative action | PLOS Medicine Skip to main content Advertisement …

ARIBA: rapid antimicrobial resistance genoty** directly from sequencing reads

M Hunt, AE Mather, L Sánchez-Busó… - Microbial …, 2017 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the major threats to human and animal health
worldwide, yet few high-throughput tools exist to analyse and predict the resistance of a …

Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement

BJ Walker, T Abeel, T Shea, M Priest, A Abouelliel… - PloS one, 2014 - journals.plos.org
Advances in modern sequencing technologies allow us to generate sufficient data to
analyze hundreds of bacterial genomes from a single machine in a single day. This potential …

Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins

NJ Croucher, AJ Page, TR Connor… - Nucleic acids …, 2015 - academic.oup.com
The emergence of new sequencing technologies has facilitated the use of bacterial whole
genome alignments for evolutionary studies and outbreak analyses. These datasets, of …

Genomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens

S Baker, N Thomson, FX Weill, KE Holt - Science, 2018 - science.org
Whole-genome sequencing (WGS) has been vital for revealing the rapid temporal and
spatial evolution of antimicrobial resistance (AMR) in bacterial pathogens. Some …

ClonalFrameML: efficient inference of recombination in whole bacterial genomes

X Didelot, DJ Wilson - PLoS computational biology, 2015 - journals.plos.org
Recombination is an important evolutionary force in bacteria, but it remains challenging to
reconstruct the imports that occurred in the ancestry of a genomic sample. Here we present …

World Health Organization Global Gonococcal Antimicrobial Surveillance Program (WHO GASP): review of new data and evidence to inform international …

M Unemo, MM Lahra, M Cole, P Galarza… - Sexual …, 2019 - CSIRO Publishing
Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a serious public health problem,
compromising the management and control of gonorrhoea globally. Resistance in N …

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis

RL Marvig, LM Sommer, S Molin, HK Johansen - Nature genetics, 2015 - nature.com
Little is known about how within-host evolution compares between genotypically different
strains of the same pathogenic species. We sequenced the whole genomes of 474 …