Enoyl acyl carrier protein reductase (InhA) is a key enzyme involved in fatty acid synthesis
mainly mycolic acid biosynthesis that is a part of NADH dependent acyl carrier protein …

Despite the adverse effects of microbial hazards on public health, major pharmaceutical
firms have left the field of anti-infective development and a dramatic reduction in the number …

Tuberculosis is an extremely serious problem of global public health. Its incidence is
worsened by the presence of multidrug-resistant (MDR) strains of Mycobacterium …

In the present work, a series of compounds containing imidazole and hydrazone structural
frameworks were synthesized and characterized using various spectral techniques …

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) affects 10 million people
each year and the emergence of resistant TB augurs for a growing incidence. In the last 60 …

Abstract Hybrid compounds with 1, 2, 4-triazole ring and a hydrazone moiety were designed
and synthesized by amine acylation of uncommon triaminogunidine derivatives using maleic …

Multidrug-resistant tuberculosis continues to pose a health security risk and remains a public
health emergency. Antimicrobial resistance result from treatment regimens that are both …

A series of pyrazole derivatives 4, 5, 6, 12, 13, 14 as well as hydrazone derivatives 7, 10, 11
were synthesized starting from adamantane-1-carbohydrazide as the bioactive core. All …

Tuberculosis remains the most deadly infectious disease worldwide due to the emergence
of drug-resistant strains of Mycobacterium tuberculosis. Hence, there is a great need for …

A new series of 4-oxothiazolidin-5-ylidene acetates (1–16) containing guanylhydrazone
moiety were designed and synthesized by using dimethyl acetylenedicarboxylate (DMAD) …