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Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
MicroRNA-based diagnosis and therapy
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …
expression. Alteration in miRNA expression results in changes in the profile of genes …
A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs
The use of microRNAs as clinical cancer biomarkers is hindered by the absence of accurate,
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
[HTML][HTML] Endometriosis-associated infertility: From pathophysiology to tailored treatment
G Bonavina, HS Taylor - Frontiers in endocrinology, 2022 - frontiersin.org
Despite the clinically recognized association between endometriosis and infertility, the
mechanisms implicated in endometriosis-associated infertility are not fully understood …
mechanisms implicated in endometriosis-associated infertility are not fully understood …
miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
Breast milk, a source of beneficial microbes and associated benefits for infant health
Human breast milk is considered the optimum feeding regime for newborn infants due to its
ability to provide complete nutrition and many bioactive health factors. Breast feeding is …
ability to provide complete nutrition and many bioactive health factors. Breast feeding is …
Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
The potential for microRNA therapeutics and clinical research
J Hanna, GS Hossain, J Kocerha - Frontiers in genetics, 2019 - frontiersin.org
As FDA-approved small RNA drugs start to enter clinical medicine, ongoing studies for the
microRNA (miRNA) class of small RNAs expand its preclinical and clinical research …
microRNA (miRNA) class of small RNAs expand its preclinical and clinical research …
Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
[HTML][HTML] miRNAs in cancer (review of literature)
B Smolarz, A Durczyński, H Romanowicz… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …