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Methods to reduce prescribing errors in elderly patients with multimorbidity
AH Lavan, PF Gallagher… - Clinical interventions in …, 2016 - Taylor & Francis
The global population of multimorbid older people is growing steadily. Multimorbidity is the
principal cause of complex polypharmacy, which in turn is the prime risk factor for …
principal cause of complex polypharmacy, which in turn is the prime risk factor for …
Managing comorbidities in COPD
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality
worldwide. Age and smoking are common risk factors for COPD and other illnesses, often …
worldwide. Age and smoking are common risk factors for COPD and other illnesses, often …
Association of off-label drug use and adverse drug events in an adult population
Importance Off-label use of prescription drugs has been identified as an important
contributor to preventable adverse drug events (ADEs) in children. Despite concerns …
contributor to preventable adverse drug events (ADEs) in children. Despite concerns …
Multiple diseases and polypharmacy in the elderly: challenges for the internist of the third millennium
A Nobili, S Garattini, PM Mannucci - Journal of comorbidity, 2011 - journals.sagepub.com
The pattern of patients admitted to internal medicine wards has dramatically changed in the
last 20–30 years. Elderly people are now the most rapidly growing proportion of the patient …
last 20–30 years. Elderly people are now the most rapidly growing proportion of the patient …
Age-related pharmacokinetic and pharmacodynamic changes and related risk of adverse drug reactions
Aging is known to be associated with an increased prevalence of multiple chronic diseases,
which frequently causes the use of complex therapeutic regimens. The aging process is …
which frequently causes the use of complex therapeutic regimens. The aging process is …
Development and validation of a score to assess risk of adverse drug reactions among in-hospital patients 65 years or older: the GerontoNet ADR risk score
Background The aim of the present study was to develop and validate a method of
identifying elderly patients who are at increased risk for an adverse drug reaction (ADR) …
identifying elderly patients who are at increased risk for an adverse drug reaction (ADR) …
VALFORTA: a randomised trial to validate the FORTA (Fit fOR The Aged) classification
M Wehling, H Burkhardt, A Kuhn-Thiel, F Pazan… - Age and …, 2016 - academic.oup.com
Trial design: to further validate the FORTA (Fit fOR The Aged) concept, a bicentric
randomised, controlled trial was run in two geriatric clinics. Methods: patients (≥ 65 years,≥ …
randomised, controlled trial was run in two geriatric clinics. Methods: patients (≥ 65 years,≥ …
The clinical implications of ageing for rational drug therapy
S Shi, K Mörike, U Klotz - European journal of clinical pharmacology, 2008 - Springer
Introduction The proportion of the elderly is constantly increasing and by the year 2025 20%
of the population will be above 65 years of age. With advanced age, subjects will develop …
of the population will be above 65 years of age. With advanced age, subjects will develop …
Polypharmacy in the elderly: can comprehensive geriatric assessment reduce inappropriate medication use?
G Sergi, MD Rui, S Sarti, E Manzato - Drugs & aging, 2011 - Springer
Polypharmacy is a problem of growing interest in geriatrics with the increase in drug
consumption in recent years, particularly among people aged> 65 years. The main reasons …
consumption in recent years, particularly among people aged> 65 years. The main reasons …
Comorbidity and repeat admission to hospital for adverse drug reactions in older adults: retrospective cohort study
Objectives To identify factors that predict repeat admission to hospital for adverse drug
reactions (ADRs) in older adults. Design Population based retrospective cohort study …
reactions (ADRs) in older adults. Design Population based retrospective cohort study …