Cells have the ability to respond to various types of environmental cues, and in many cases
these cues induce directed cell migration towards or away from these signals. How cells …

Directional cell migration normally relies on a variety of external signals, such as chemical,
mechanical, or electrical, which instruct cells in which direction to move. Many of the major …

INTRODUCTION Cells migrate over long distances during normal embryonic development
and in disease, and they navigate through complex, branched paths. Chemotaxis, cell …

Immune responses rely on the rapid and coordinated migration of leukocytes. Whereas it is
well established that single-cell migration is often guided by gradients of chemokines and …

In bacterial communities, cells often communicate by the release and detection of small
diffusible molecules, a process termed quorum-sensing. Signal molecules are thought to …

Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …

Cancer cell invasion through physical barriers in the extracellular matrix (ECM) requires a
complex synergy of traction force against the ECM, mechanosensitive feedback, and …

Simple Summary Due to the broad functions of Toll-like receptor 2 (TLR2) in innate
immunity, the drive for the development of TLR2-targeted therapeutic treatments has …

Cell polarization is a key step in the migration, development, and organization of eukaryotic
cells, both at the single cell and multicellular level. Research on the mechanisms that give …