The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host

JD Maya, BK Cassels, P Iturriaga-Vásquez… - … and Physiology Part A …, 2007 - Elsevier
Current knowledge of the biochemistry of Trypanosoma cruzi has led to the development of
new drugs and the understanding of their mode of action. Some trypanocidal drugs such as …

Antimicrobial Peptides with Anti-Candida Activity

A Perez-Rodriguez, E Eraso, G Quindós… - International journal of …, 2022 - mdpi.com
Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is
the most usual, presenting a high morbidity and mortality. Candida albicans remains the …

Antimicrobial peptides from hylid and ranin frogs originated from a 150‐million‐year‐old ancestral precursor with a conserved signal peptide but a hypermutable …

D Vanhoye, F Bruston, P Nicolas… - European journal of …, 2003 - Wiley Online Library
The dermal glands of frogs produce antimicrobial peptides that protect the skin against
noxious microorganisms and assist in wound repair. The sequences of these peptides are …

Host-defence peptides from the glandular secretions of amphibians: structure and activity

TL Pukala, JH Bowie, VM Maselli, IF Musgrave… - Natural product …, 2006 - pubs.rsc.org
Covering: up to the end of 2005 This review covers the literature on the subject of
biologically active peptides from the glands of amphibians. These include neuropeptides …

[PDF][PDF] Antimicrobial peptides from frog skin: biodiversity and therapeutic promises

A Ladram, P Nicolas - Front. Biosci, 2016 - article.imrpress.com
More than a thousand antimicrobial peptides (AMPs) have been reported in the last decades
arising from the skin secretion of amphibian species. Generally, each frog species can …

[HTML][HTML] Solution NMR studies of amphibian antimicrobial peptides: linking structure to function?

EF Haney, HN Hunter, K Matsuzaki, HJ Vogel - Biochimica et Biophysica …, 2009 - Elsevier
The high-resolution three-dimensional structure of an antimicrobial peptide has implications
for the mechanism of its antimicrobial activity, as the conformation of the peptide provides …

Bioinformatic analysis of 1000 amphibian antimicrobial peptides uncovers multiple length-dependent correlations for peptide design and prediction

G Wang - Antibiotics, 2020 - mdpi.com
Amphibians are widely distributed on different continents, except for the polar regions. They
are important sources for the isolation, purification and characterization of natural …

Antimicrobial peptide action on parasites

M Torrent, D Pulido, L Rivas, D Andreu - Current drug targets, 2012 - ingentaconnect.com
Diseases caused by protozoan parasites can pose a severe thread to human health and are
behind some serious neglected tropical diseases like malaria and leishmaniasis. Though …

[HTML][HTML] The dermaseptin superfamily: a gene-based combinatorial library of antimicrobial peptides

P Nicolas, C El Amri - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2009 - Elsevier
Skin secretions of hylid frogs show amazing levels of interspecific and intraspecific diversity
and are comprised of a cocktail of genetically-related, but markedly diverse antimicrobial …