Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Osteoimmunology is at full display during endosseous implant osseointegration. Bone
formation, maintenance and resorption at the implant surface is a result of bidirectional and …

Although biodegradable polymer coatings can impede corrosion of magnesium (Mg)-based
orthopedic implants, they are prone to excessive degradation and accidental scratching in …

Body implants and implantable medical devices have dramatically improved and prolonged
the life of countless patients. However, our body repair mechanisms have evolved to isolate …

A coordinated interaction between osteogenesis and osteoimmune microenvironment is
essential for successful bone healing. In particular, macrophages play a central regulatory …

The excessive accumulation of reactive oxygen species (ROS) under osteoporosis
precipitates a microenvironment with high levels of oxidative stress (OS). This could …

Owing to their self‐renewal and differentiation ability, stem cells are conducive for repairing
injured tissues, making them a promising source of seed cells for tissue engineering. The …

Bone regeneration remains a critical concern across diverse medical disciplines, because it
is a complex process that requires a combinatorial approach involving the integration of …

Bone defect repair at load-bearing sites is a challenging clinical problem for orthopedists.
Defect reconstruction with implants is the most common treatment; however, it requires the …

Magnesium (Mg)-based orthopedic implant materials can potentially be protected from
deterioration using a protective polymer coating. However, this coating is susceptible to …