Pathogenesis of glucocorticoid-induced osteoporosis and options for treatment

P Chotiyarnwong, EV McCloskey - Nature Reviews Endocrinology, 2020 - nature.com
Glucocorticoids are widely used to suppress inflammation or the immune system. High
doses and long-term use of glucocorticoids lead to an important and common iatrogenic …

Osteoporosis and fractures in women: the burden of disease

M Lorentzon, H Johansson, NC Harvey, E Liu… - …, 2022 - Taylor & Francis
Osteoporosis is a disease characterized by impaired bone microarchitecture and reduced
bone mineral density (BMD) resulting in bone fragility and increased risk of fracture. In …

Treating the Side Effects of Exogenous Glucocorticoids; Can We Separate the Good From the Bad?

R Pofi, G Caratti, DW Ray, JW Tomlinson - Endocrine Reviews, 2023 - academic.oup.com
It is estimated that 2% to 3% of the population are currently prescribed systemic or topical
glucocorticoid treatment. The potent anti-inflammatory action of glucocorticoids to deliver …

Glucocorticoids and bone: consequences of endogenous and exogenous excess and replacement therapy

RS Hardy, H Zhou, MJ Seibel, MS Cooper - Endocrine reviews, 2018 - academic.oup.com
Osteoporosis associated with long-term glucocorticoid therapy remains a common and
serious bone disease. Additionally, in recent years it has become clear that more subtle …

Glucocorticoid-induced osteoporosis: 2019 concise clinical review

G Adami, KG Saag - Osteoporosis International, 2019 - Springer
Glucocorticoids remain widely used for many medical conditions, and fractures are the most
serious common adverse event related to long-term glucocorticoid use. Glucocorticoid …

Prevention and treatment of glucocorticoid-induced osteoporosis in adults: consensus recommendations from the Belgian bone club

MR Laurent, S Goemaere, C Verroken… - Frontiers in …, 2022 - frontiersin.org
Glucocorticoids are effective immunomodulatory drugs used for many inflammatory
disorders as well as in transplant recipients. However, both iatrogenic and endogenous …

Comparative effectiveness and cardiovascular safety of romosozumab versus teriparatide in patients with osteoporosis: a population-based cohort study

S Masuda, T Fukasawa, S Matsuda, S Yoshida… - Osteoporosis …, 2024 - Springer
This study compared the effectiveness and cardiovascular safety of romosozumab and
teriparatide. The main finding was that there were no significant differences between the two …

Glucocorticoid-induced osteoporosis update

G Adami, KG Saag - Current Opinion in Rheumatology, 2019 - journals.lww.com
Glucocorticoid-induced osteoporosis update : Current Opinion in Rheumatology
Glucocorticoid-induced osteoporosis update : Current Opinion in Rheumatology Log in or …

Combination therapy of PTH and antiresorptive drugs on osteoporosis: a review of treatment alternatives

C Zhang, C Song - Frontiers in Pharmacology, 2021 - frontiersin.org
Antiresorptive drugs have been widely used for osteoporosis. Intermittent parathyroid
hormone (PTH), an anabolic agent, increases osteoblast production rate and inhibits …

A bone targeting nanoparticle loaded ogp to restore bone homeostasis for osteoporosis therapy

S Ma, S Xu, M Li, Y Du, G Tian, J Deng… - Advanced …, 2023 - Wiley Online Library
Restoring bone homeostasis is the key to the treatment of osteoporosis. How to increase
osteogenic ability or inhibit osteoclast activity has always been a topic of great concern. In …