[HTML][HTML] The role of stakeholders' understandings in emerging antimicrobial resistance: A one health approach

P Nardulli, A Ballini, M Zamparella, D De Vito - Microorganisms, 2023‏ - mdpi.com
The increasing misuse of antibiotics in human and veterinary medicine and in
agroecosystems and the consequent selective pressure of resistant strains lead to multidrug …

Revisiting the role of genetic variation in adaptation

D Agashe, M Sane, S Singhal - The American Naturalist, 2023‏ - journals.uchicago.edu
Evolutionary biologists have thought about the role of genetic variation during adaptation for
a very long time—before we understood the organization of the genetic code, the …

Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails

D Garcia Castillo, N Barton, R Faria, J Larsson… - Science …, 2024‏ - science.org
Predicting the outcomes of adaptation is a major goal of evolutionary biology. When
temporal changes in the environment mirror spatial gradients, it opens up the potential for …

Eco‐evolution from deep time to contemporary dynamics: the role of timescales and rate modulators

EA Fronhofer, D Corenblit, JN Deshpande… - Ecology …, 2023‏ - Wiley Online Library
Eco‐evolutionary dynamics, or eco‐evolution for short, are often thought to involve rapid
demography (ecology) and equally rapid heritable phenotypic changes (evolution) leading …

Distinguishing mutants that resist drugs via different mechanisms by examining fitness tradeoffs

K Schmidlin, S Apodaca, D Newell, A Sastokas… - Elife, 2024‏ - elifesciences.org
There is growing interest in designing multidrug therapies that leverage tradeoffs to combat
resistance. Tradeoffs are common in evolution and occur when, for example, resistance to …

Game theory for managing evolving systems: Challenges and opportunities of including vector-valued strategies and life-history traits

M Kleshnina, S Streipert, JS Brown… - Dynamic Games and …, 2023‏ - Springer
Nature exhibits rapid evolution in response to human activities. When using natural
resources for their own profit, humans should account for such responses. Stackelberg …

Substrate geometry affects population dynamics in a bacterial biofilm

W Postek, K Staśkiewicz, E Lilja, B Wacław - Proceedings of the National …, 2024‏ - pnas.org
Biofilms inhabit a range of environments, such as dental plaques or soil micropores, often
characterized by noneven surfaces. However, the impact of surface irregularities on the …

Quantitative systems-based prediction of antimicrobial resistance evolution

DA Charlebois - NPJ Systems Biology and Applications, 2023‏ - nature.com
Predicting evolution is a fundamental problem in biology with practical implications for
treating antimicrobial resistance, which is a complex system-level phenomenon. In this …

Unravelling the factors of evolutionary repeatability: insights and perspectives on predictability in evolutionary biology

SM Pearless, NE Freed - Frontiers in Ecology and Evolution, 2024‏ - frontiersin.org
Evolutionary biology was previously considered a historical science with predictions about
evolutionary trajectories believed to be near impossible. The development of high …

Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation

M Roesti, H Roesti, I Satokangas… - Cold Spring …, 2024‏ - cshperspectives.cshlp.org
Accurate predictions are commonly taken as a hallmark of strong scientific understanding.
Yet, we do not seem capable today of making many accurate predictions about biological …