Identity matters: cancer stem cells and tumour plasticity in head and neck squamous cell carcinoma

A Salem, T Salo - Expert reviews in molecular medicine, 2023 - cambridge.org
Head and neck squamous cell carcinoma (HNSCC) represents frequent yet aggressive
tumours that encompass complex ecosystems of stromal and neoplastic components …

Neuronal-activity dependent mechanisms of small cell lung cancer progression

S Savchuk, K Gentry, W Wang, E Carleton, B Yalçın… - bioRxiv, 2023 - biorxiv.org
Neural activity is increasingly recognized as a critical regulator of cancer growth. In the
brain, neuronal activity robustly influences glioma growth both through paracrine …

[HTML][HTML] Deciphering the Blood–Brain Barrier Paradox in Brain Metastasis Development and Therapy

JJ Peters, C Teng, K Peng, X Li - Cancers, 2025 - mdpi.com
Gatekeeper or accomplice? That is the paradoxical role of the blood–brain barrier (BBB) in
develo** brain metastasis (BM). BM occurs when cancerous cells from primary cancer …

Small cell lung cancer plasticity enables NFIB-independent metastasis

JH Ko, KE Lambert, D Bhattacharya, MC Lee… - Cancer …, 2024 - aacrjournals.org
Metastasis is a major cause of morbidity and mortality in patients with cancer, highlighting
the need to identify improved treatment and prevention strategies. Previous observations in …

[HTML][HTML] Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry

SM Pearsall, SC Williamson, S Humphrey… - Journal of Thoracic …, 2023 - Elsevier
Introduction Vasculogenic mimicry (VM), the process of tumor cell trans-differentiation to
endow endothelial-like characteristics supporting de novo vessel formation, is associated …

[KİTAP][B] Investigating Drivers of Small Cell Lung Cancer Progression and Metastasis

J Ko - 2023 - search.proquest.com
Most cancer patients die from the development of metastatic disease; however, the
molecular mechanisms underlying metastatic progression remain poorly understood. Small …