Mesenchymal stem cells: cell fate decision to osteoblast or adipocyte and application in osteoporosis treatment

L Hu, C Yin, F Zhao, A Ali, J Ma, A Qian - International Journal of …, 2018 - mdpi.com
Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …

[HTML][HTML] CRISPR/Cas9-engineered mesenchymal stromal/stem cells and their extracellular vesicles: A new approach to overcoming cell therapy limitations

A Hazrati, K Malekpour, S Soudi… - Biomedicine & …, 2022 - Elsevier
Cell therapy is one of the newest therapeutic approaches for treating tissue destruction
diseases and replacing damaged parts in defective tissues. Among different cells …

[HTML][HTML] Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds

ARMR Amin, PA Karpowicz, TE Carey, J Arbiser… - Seminars in cancer …, 2015 - Elsevier
The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to
continue to proliferate, cancer cells must somehow uncouple themselves from the many …

Osteoporosis: the current status of mesenchymal stem cell-based therapy

J Phetfong, T Sanvoranart, K Nartprayut… - Cellular & molecular …, 2016 - Springer
Osteoporosis, or bone loss, is a progressive, systemic skeletal disease that affects millions of
people worldwide. Osteoporosis is generally age related, and it is underdiagnosed because …

Acrylated epoxidized soybean oil/hydroxyapatite-based nanocomposite scaffolds prepared by additive manufacturing for bone tissue engineering

D Mondal, A Srinivasan, P Comeau, YC Toh… - Materials Science and …, 2021 - Elsevier
The mechanical properties and biocompatibility of nanocomposites composed of Acrylated
Epoxidized Soybean Oil (AESO), nano-Hydroxyapatite (nHA) rods and either 2-Hydroxyethyl …

[HTML][HTML] In vitro augmentation of mesenchymal stem cells viability in stressful microenvironments

F Amiri, A Jahanian-Najafabadi… - Cell stress and …, 2015 - Elsevier
Mesenchymal stem cells (MSCs) are under intensive investigation for use in cell-based
therapies because their differentiation abilities, immunomodulatory effects, and homing …

Soliciting strategies for develo** cell-based reference materials to advance mesenchymal stromal cell research and clinical translation

S Viswanathan, A Keating, R Deans… - Stem cells and …, 2014 - liebertpub.com
The mesenchymal stromal cell (MSC) field continues to rapidly progress with a number of
clinical trials initiated and completed, with some reported successes in multiple clinical …

Assessment of tumorigenic potential in mesenchymal-stem/stromal-cell-derived small extracellular vesicles (MSC-sEV)

TT Tan, RC Lai, J Padmanabhan, WK Sim, ABH Choo… - Pharmaceuticals, 2021 - mdpi.com
Mesenchymal-stem/stromal-cell-derived small extracellular vesicles (MSC-sEV) have been
shown to ameliorate many diseases in preclinical studies. However, translating MSC-sEV …

[HTML][HTML] Stress-induced senescence in mesenchymal stem cells: Triggers, hallmarks, and current rejuvenation approaches

SS Lee, TT Vũ, AS Weiss, GC Yeo - European Journal of Cell Biology, 2023 - Elsevier
Mesenchymal stem cells (MSCs) have emerged as promising cell-based therapies in the
treatment of degenerative and inflammatory conditions. However, despite accumulating …

Therapeutic application of mesenchymal stem cells in bone and joint diseases

Y Liu, J Wu, Y Zhu, J Han - Clinical and experimental medicine, 2014 - Springer
Mesenchymal stem cells (MSCs), the non-hematopoietic progenitor cells, are multi-potent
stem cells from a variety of tissues with the capability of self-renewal, proliferation …